住院精神病患者罹患代谢综合征现状调查

目的 探讨住院精神病患者罹患代谢综合征的发生率及其相关影响因素.方法 对327例住院精神病患者的一般人口学资料、近1个月血脂水平、空腹血糖和血压状况等进行调查.依据2005年国际糖尿病联盟提出的代谢综合征定义筛查罹患代谢综合征的发生率,并进行相关分析.结果 本组患者罹患代谢综合征检出率为33.90%.其中年龄≥40岁者代谢综合征检出率(38.33%)显著高于年龄＜40岁者(24.00%),住院时间≥84 d者(37.60%)显著高于住院时间＜84 d者(22.08%),差异均有显著性(χ2=6.089、6.326,P＜0.05);共病糖尿病(73 17%)、高血压(66.67%)、高脂血症(77.5%)患者代谢综合征检出率均显著高于无共病者(28 32%、26.59%、27.87%),差异均有极显著性(χ2=32.168、35.090、38.559,P＜0.01).Logistic回归分析显示,精神病患者共病糖尿病、高血压、高脂血症、甘油三酯升高、高密度脂蛋白降低、空腹血糖异常、腹型肥胖等因素为罹患代谢综合征的危险因素.结论 住院精神病患者罹患代谢综合征发生率显著增高,其中共病糖尿病、高血压、高脂血症、甘油三酯升高、高密度脂蛋白降低、空腹血糖异常、腹型肥胖等因素是罹患代谢综合征的危险因素.

Surveys of hospitalized mental patients suffered from metabolic syndrome

Objective To explore the incidence of metabolic syndrome and relative influencing factors in hospitalized mental patients. Methods Surveys were carried out of general demographic data, blood fat levels of near 1 month, blood-fasting sugar and BP status etc. in 327 hospitalized psychosis patients. The incidence of metabolic syndrome was screened according to the definition of metabolic syndrome advanced by International Diabetes Federation 2005 and correlatively analyzed. Results The detection rate of metabolic syndrome was 33.90%. The detection rate of metabolic syndrome was significantly higher among patients aged ≥40 than among ones 〈40 （38.33% vs. 24.00%） and among patients with ≥84 day hospitalization than ones 〈84 （37.60% vs. 22.08%）, differences were significant （X2=6. 089, 6. 326,P〈0.05） ; the detection rates were significantly higher among patients with comorbid diabetes （73.17%）, hypertension （66.67%） and hyperlipidemia （77.5%） than among ones without （28.32%, 26. 59%, 27. 87%）, differences were very significant （x2 = 32. 168, 35.090, 38.559, P 〈 0.01 ）. Logistic regression analysis showed that risk factors inducing metabolic syndrome were comorbid diabetes, hypertension and hyperlipidemia triglyceride elevation, loe level of HDL, blood-fasting sugar abnormality, abdominal obesity and so on. Conclusion The incidence of metabolic syndrome increases notably in hospitalized psychosis patients; risk factors inducing metabolic syndrome are comorbid diabetes, hypertension and hyperlipidemia triglyceride elevation, loe level of HDL, blood-fasting sugar abnormality, abdominal obesity and so on.