经尿道等离子双极电切治疗不同体积BPH对比分析

目的：对比分析经尿道等离子双极电切术（PKRP）治疗大体积（〉80ml）良性前列腺增生（BPH）的疗效与安全性。方法：2009年6月～2011年1月间行PKRP术治疗BPH患者52例，按前列腺体积分为〉80ml组和〈80ml组，每组26例。术后随访3～14个月。结果：〉80ml组国际前列腺症状评分（IPSS）、刺激症状评分（IPSS1）、梗阻症状评分（IPSS2）分别由术前的（19．85±6．534）、（8．73±3．054）、（11．12±4．484）下降至术后的（7．38±4．964）、（4．88±3．421）、（2．50±2．502）（P〈0．01）。〈80ml组分别由术前的（21．04±6．453）、（9．00±3．225）、（12．04±4．556）下降至术后的（6．27±3．811）、（4．69±3．185）、（1．58±2．301）（P〈0．01）。3项指标术前、术后数值分别进行两组间对比，差异均无统计学意义（P〉0．05）。〉80ml组平均手术时间106．15min，平均切除前列腺质量58．64g；〈80ml组分别为60．19min、30．00g，差异存在统计学意义（P〈0．01），余两组术中出血量、术后膀胱冲洗时间，留置尿管时间、术后住院天数差异均无统计学意义（P〉0．05）。〉80ml组术中或术后输血患者5例，〈80ml组1例。两组均无经尿道电切综合征（TURS）发生。结论：PKRP术治疗大体积（〉80ml）BPH安全、有效，且手术效果和安全性与治疗〈80ml的BPH相似。

Comparative Analysis of the Efficacy and Safety of Transurethral Plasmakinetic Resection of the Prostate for Treatment of Benign Prostatic Hyperplasia of Different Volumes

Objeetive：A retrospective study was conducted to perform a comparative analysis of the efficacy and safety of transurethral plasmakinetic resection of the prostate（PKRP） for treatment of benign prostatic hyperplasia （BPH） of large volume（〉80 ml）. Methods：52 patients with BPH who underwent PKRP between June 2009 and Jan 2011 were divided into 2 groups according to the prostate volume （group1, 〉80 ml; group2, 〈80 ml）, each group conl：ains 26 cases, the patients were followed up for 3 - 14 months postoperatively. Results：In group1, the av- erage IPSS,IPSS1 ,IPSS2 decreased from （19.85±6. 534）, （8.73±3. 054）, （11.12±4. 484） preoperatively to （7. 38±4. 964）, （4.88±3. 421）, （2.50±2. 502） postoperative （P〈0.01）. In group2,the average IPSS,IPSS1 ,IPSS2 decreased from （21.04 ± 6. 453）, （9.00±3. 225）, （ 12.04 ±4. 556） preoperatively to （ 6.27 ±3. 811 ）, （4. 69 ± 3. 185） ,（1.58±2. 301） postoperatively （P〈0.01）. The 3 indices mentioned above showed no differences between the two groups preoperatively and postoperatively （P〉0.05）. A statically significant difference was found in terms of total operative time and resected prostate tissue weight （P〈0.01）, while the intraoperative bleeding, irrigation time, catheterization duration, and postoperative admission duration were comparable between the two groups. Concerning the eomplications,5 eases of blood transfusion occurred in groupl,in group2,the number was 1. No transurethral resection syndrome occurred in both groups. Conelusions：PKRP seems to be a safe and effec- tive treatment for relief of symptoms of BPH in patients with large volume prostate glands （〉80 ml） ,and the efficacy and safety of surgery is similar to that of the surgery for patients of BPH with 〈80 ml prostate glands.