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CD8+淋巴细胞表达强度与乙型病毒性肝炎不同肝组织炎症分级的关系
引用本文:陆忠华,裴浩,居朝霞,丁虹. CD8+淋巴细胞表达强度与乙型病毒性肝炎不同肝组织炎症分级的关系[J]. 传染病信息, 2006, 19(3): 137-138,160
作者姓名:陆忠华  裴浩  居朝霞  丁虹
作者单位:江苏无锡市传染病医院,无锡,214007;江苏无锡市传染病医院,无锡,214007;江苏无锡市传染病医院,无锡,214007;江苏无锡市传染病医院,无锡,214007
摘    要:目的探讨CD8 淋巴细胞与乙型肝炎患者肝组织炎症分级的关系和意义。方法应用免疫组织化学技术,检测不同炎症分级的肝组织中CD8 淋巴细胞的表达。结果G0肝组织中CD8 表达弱,随着炎症分级的增强,CD8 表达逐渐增强。G4最为明显,有明显统计学意义。结论CD8 淋巴细胞表达强度与肝组织炎症分级有明显相关性。

关 键 词:肝组织炎症分级  CD8+淋巴细胞  免疫组织化学染色
文章编号:1007-8134(2006)03-0137-03
收稿时间:2006-02-28
修稿时间:2006-06-15

Relationship between expression of CD8+ lymphocyte and different inflammation grades in liver tissues from patients with hepatitis B
Lu Zhonghua, Pei Hao, Ju Zhaoxia,et al.. Relationship between expression of CD8+ lymphocyte and different inflammation grades in liver tissues from patients with hepatitis B[J]. Infectious Disease Information, 2006, 19(3): 137-138,160
Authors:Lu Zhonghua   Pei Hao   Ju Zhaoxia  et al.
Affiliation:Lu Zhonghua, Pei Hao, Ju Zhaoxia, et al.
Abstract:Objective To investigate the expression and significance of CD8 lymphocyte in liver tissues with different inflammatory grades of hepatitis B. Method The expression of CD8 lymphocytes was evaluated with immunohistochemistry in liver tissues of different inflammatory grades from the patients with viral hepatitis B. Results In liver tissues with inflammatory activity of G0, the CD8 lymphocytes presented low expression. The higher inflammatory grade was in liver tissues, the more numbers of CD8 lymphocytes there would be. The expression of CD8 lymphocytes in G4 liver tissues was the most apparent, which had obvious statistically signficance. Conclusion The expression of CD8 lymphocytes in liver is closely associated with histological activity grades in chronic hepatitis B.
Keywords:liver tissue inflammation grade  CD8 lymphocyte  immunohistochemisty staining
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