妊娠高血压疾病剖宫产患者超敏C反应蛋白水平变化及临床意义

目的：探讨妊娠高血压疾病剖宫产患者在手术前后超敏C反应蛋白（hs—CRP）的水平变化及其临床意义。方法：选取106例妊娠高血压疾病剖宫产患者（轻型组60例、重型组46例）纳入研究,同时设60例正常血压剖宫产患者作为正常对照组,测定剖宫产手术前、手术后第一天及第五天的hs-CRP、白细胞计数及中性粒细胞比率。结果：与正常血压剖宫产患者比较,妊娠高血压疾病剖宫产患者的hs-CRP手术前后均有升高,特别是重型组（P〈0．05）。白细胞及中性粒细胞变化不如hs-CRP明显。结论：hs—CRP水平的变化与妊娠高血压疾病的病情程度密切相关,比传统的血常规检测更加灵敏。对观察病情变化及评估妊娠高血压疾病剖宫产患者的预后具有重要的临床意义。

Change of High sensitivity C-reactive protein and its clinic significance in cesarean section patients with gestational hypertension

Objective：To discuss the change before and after the operation of high sensitivity C--reactive protein and its clinic significance in cesarean section patients with gestational hypertension. Methods：Selected 106 cases of cesarean section patients with gestational hypertension （mild, 60 ;severe 46） ,and 60 cases of cesarean section patients with normal blood pressure as the control group. High sensitivity C-reactive protein , white blood cell and neutrophil level were detected before operation, the first clay and the fifth day after operation. Results：Compared with noral group, high sensitivity C--reactive protein level increased in cesarean section patients with gestationai hypertension, especially in severe group（P〈0.05）. Changes of high sensitivity C-reactive protein are higher than that in white blood cell and neutrophil. Conclusion：The level of high sensitivity C-reactive protein is associated with the course of cesarean section patients with gestational hypertension ,which is more sensitive than the tranditional routine blood test. It is very important to observe the diseases and evaluate the outcomes of cesarean section patients with gestational hypertension.