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Sensitivity to ethidium bromide during meiosis in Saccharomyces cerevisiae
Authors:S. L. Kelly  J. M. Parry
Affiliation:(1) Department of Genetics, University College of Swansea, SA2 8PP Singleton Park, Swansea, UK;(2) Wolfson Institute of Biotechnology, University of Sheffield, SIO 2TN Sheffield, UK
Abstract:
Summary Ethidium bromide was found to inhibit nuclear and mitochondrial DNA synthesis during meiosis which resulted in the inhibition of meiotic gene conversion and sporulation and was also lethal. Protection from the effects of ethidium bromide on meiotic gene conversion and survival was found to coincide with DNA synthesis, but it is possible that protection from sporulation inhibition occurs only later in meiosis.
Keywords:Yeast  Ethidium bromide  Meiosis
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