肿瘤标志物对胰腺癌诊断及预后评估作用的研究进展

胰腺癌是目前常见的恶性肿瘤,其发病率与致死率近乎持平。如何提高胰腺癌早期确诊率和胰腺癌的治疗效果是急需解决的问题。肿瘤标志物对胰腺癌患者的筛选、治疗效果评估和监测术后复发的作用正在不断扩大。笔者通过回顾胰腺癌血清和胰液等体液中的肿瘤标志物的研究进展及存在的问题,重点探讨肿瘤标志物对胰腺癌诊断及预后评估的作用。

Research progress of tumor markers for diagnosis and prognosis estimation of pancreatic cancer

Pancreatic cancer is a common malignant tumor currently, and its mortality is nearly equal to its morbidity. How to improve early diagnosis and treatment efficiency of pancreatic cancer has become an urgent issue. The role of tumor markers in screening patients with pancreatic cancer, assessing treatment efficacy and detecting postoperative recurrence has become increasingly important. In this paper, the authors mainly discuss the role of tumor markers for diagnosis and prognosis estimation of pancreatic cancer through reviewing the research progress of tumor makers in the body fluids such as the blood serum and pancreatic juice of pancreatic cancer patients and current problems.