| 感染性胰腺坏死的病原学研究进展 |
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| 引用本文： | 武玉多 综述 李非,曹峰,高崇崇 审校.感染性胰腺坏死的病原学研究进展[J].中国普通外科杂志,2018,27(9):1187-1191. |
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| 作者姓名： | 武玉多 综述 李非 曹峰 高崇崇 审校 |
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| 作者单位： | 首都医科大学宣武医院普通外科 |
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| 基金项目： | 首都临床特色应用研究与成果推广基金资助项目（Z171100001017077）。 |
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| 摘 要： | 感染性胰腺坏死(IPN)是急性胰腺炎的严重并发症,也是患者死亡的主要原因。微创行胰腺坏死组织清除配合抗菌素是目前IPN治疗的主要方式。IPN多为院内获得性感染,菌谱复杂,多重耐药菌常见,抗菌素选择困难。目前,针对IPN患者病原菌及耐药性的临床资料有限,所以了解其发病的危险因素,细菌谱,耐药性及相关预后可以对患者进行更佳的诊治。
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| 关 键 词： | 胰腺炎，急性坏死性 病灶感染 危险因素 预后 综述文献 |
| 收稿时间： | 2018/1/19 0:00:00 |
| 修稿时间： | 2018/7/22 0:00:00 |
Research progress of pathogenesis of infected pancreatic necrosis |
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| WU Yuduo,LI Fei,CAO Feng,GAO Chongchong.Research progress of pathogenesis of infected pancreatic necrosis[J].Chinese Journal of General Surgery,2018,27(9):1187-1191. |
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| Authors: | WU Yuduo LI Fei CAO Feng GAO Chongchong |
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| Institution: | (Department of General Surgery, Xuanwu Hospital Capital Medical University, Beijing 100053, China) |
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| Abstract: | Infected pancreatic necrosis (IPN) is a serious complication of acute pancreatitis and it is also a leading cause of death. Minimally invasive debridement of the necrotic pancreatic tissue combined with antibiotics is currently the main treatment method for IPN. IPN is mostly involving hospital-acquired infections, with complex spectrum, frequent multidrug-resistant bacteria, and difficult choice of antibiotics. At present, the clinical data on the pathogens and drug resistance of IPN patients are limited, so understanding the risk factors for its occurrence, bacterial spectrum, drug resistance and related prognosis can provide better diagnosis and treatment for these patients. |
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| Keywords: | Pancreatitis Acute Necrotizing Focal Infection Risk factors Prognosis Review |
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