多囊卵巢综合征患者体成分与代谢综合征的相关性分析

目的 了解多囊卵巢综合征(PCOS)患者体成分与代谢综合征(MS)的特点.方法 对336例PCOS患者检测进行生殖内分泌、糖、脂代谢指标检测,并利用肌肉功能分析系统测量全身和局部身体成分.结果 PCOS患者MS发生率为18.8％ (63/336),且随全身脂肪百分比和脂质蓄积指数增加而增加,育龄期MS发生率明显高于青春期.PCOS合并MS者体脂各项指标、肌肉分布系数、年龄、血糖、血清胰岛素、血脂及血压均高于非MS组,双下肢肌力(MSL/MSR)低于非MS组,但睾酮无明显差异.结论 随着全身脂肪百分比、年龄和脂质蓄积指数的增加,PCOS患者MS的危险增加.

Association of fat distribution with metabolic syndrome in patients with polycystic ovary syndrome

Objective To study the characteristics of the metabolic syndrome(MS) in patients with polycystic ovary syndrome(PCOS).Methods Oral glucose tolerance test(OGTT) was performed in 336 patients with PCOS,and the serum levels triglycerides(TG),total cholesterol,high-density lipoprotein cholesterol,low-density lipoprotein cholesterol and testosterone were measured.Results The total incidence of MS was 18.8% in these 336 patients with PCOS.The incidence of MS increased with percent body fat(%BF) and lipid accumulation product(LAP) in patients with PCOS.The patients at child-bearing age appeared to have a higher incidence of MS than those in puberty.The muscle distribution coefficient,age,body mass index,and the metabolic parameters were all higher in patients with MS than in those without MS.The bilateral lower limb muscle strength were lower in patients with MS than in those without,but the level of testosterone showed no significant difference between them.Conclusion The risk of MS increases with BF%,age and LAP in patients with PCOS.