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非小细胞肺癌脏器转移数目对预后的影响
引用本文:徐刚,李永恒,朱广迎,徐博. 非小细胞肺癌脏器转移数目对预后的影响[J]. 中国肿瘤, 2009, 9(1): 72-74
作者姓名:徐刚  李永恒  朱广迎  徐博
作者单位:北京大学临床肿瘤学院、北京肿瘤医院暨北京市肿瘤防治研究所,恶性肿瘤发病机制及转化研究教育部重点实验室,北京,100036
摘    要:[目的]探讨非小细胞肺癌脏器转移数目对生存期的影响。[方法]回顾分析非小细胞肺癌238例,转移出现时间、部位、数目对生存期影响。[结果]生存分析显示,患病期间脏器转移总数目,初诊时脏器转移的数目,首发转移时转移脏器数目对生存影响显著(P分别为0.0095,0.0001和0.0001)。COX分析提示初诊和首发脏器转移数目是独立预后因素(P分别为0.001,0.02)。[结论]脏器转移的数目对非小细胞肺癌的预后有影响。

关 键 词:非小细胞肺癌  肿瘤转移  预后

Impact of the Number of Metastastatic Organ on Prognosis in Non-small Cell Lung Cancer
Affiliation:XU Gang, LI Yong-heng, ZHU Guang-ying, et al. (Peking University School of Oncology, Beijing Cancer Hospital Institute, Beijing 100036 China)
Abstract:[Purpose] To ivestigate the effect of organ metastasis number on survival of non-smaU cell lung cancer (NSCLC). [Methods] The effect of metastatic time, site, number on survival of 238 cases with NSCLC were analyzed retrospectively. [Results ] The total metastatic organ number, and the metastatic number at initial diagnosis or at first metastasis had significant influence on survival (P=0.0095,0.0001,0.0001). COX analysis showed the number of organ metastasis at initial diagnosis, or at first organ metastasis was independent prognosis factor (P=0.001 and 0.02 respectively). [Conclusion ] The metastasis number has influence on prognosis of NSCLC.
Keywords:non-small cell lung cancer  neoplasm metastasis  prognosis
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