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间质性肺疾病与肺癌
引用本文:刘健群,代华平. 间质性肺疾病与肺癌[J]. 国际呼吸杂志, 2011, 31(22): 1741-1745. DOI: 10.3760/cma.j.issn.1673-436X.2011.022.014
作者姓名:刘健群  代华平
作者单位:1. 北京丰台医院
2. 100020 北京呼吸疾病研究所;北京市呼吸和肺循环疾病实验室;首都医科大学附属北京朝阳医院呼吸与危重症医学科
摘    要:间质性肺疾病(ILD)患者中肺癌的发病率增高,特别是特发性肺纤维化合并肺癌的报道最多.ILD合并肺癌的病理类型以鳞状细胞癌最多,好发于肺下叶和外周部位.ILD的一些肿瘤标记物增高,与疾病的活动程度、严重程度、肺纤维化程度和病情预后等有关,并且具有一定的诊断价值.ILD的肿瘤标记物增高可能是其合并肺癌的危险因素.本文对I...

关 键 词:间质性肺疾病  特发性肺纤维化  肺肿瘤  肿瘤标记物

Interstitial lung disease and lung cancer
LIU J ian-qun,DAI Hua-ping. Interstitial lung disease and lung cancer[J]. International Journal of Respiration, 2011, 31(22): 1741-1745. DOI: 10.3760/cma.j.issn.1673-436X.2011.022.014
Authors:LIU J ian-qun  DAI Hua-ping
Abstract:A number of studies have shown a high incidence of lung cancer in patients with interstitial lung disease (ILD),especially idiopathic pulmonary fibrosis.The most pathological type of ILD combined with lung cancer is squamous cell carcinoma,and it usually occurs in the lower lobes and peripheral parts.The increase of some tumor markers of ILD is associated with the degree of disease activity,severity,fibrosis,prognosis and so on,and it has a certain diagnostic value.The increase of ILD tumor markers may be the risk factors of ILD combined with lung cancer.This paper makes a review on the epidemiological study of ILD combined with lung cancer and the research progress of ILD tumor markers.
Keywords:Interstitial lung disease  Idiopathic pulmonary fibrosis  Lung neoplasm  Tumor marker
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