| 阻塞性睡眠呼吸暂停低通气综合征与胰岛β细胞功能障碍 |
| |
| 引用本文： | 卢巍,康健. 阻塞性睡眠呼吸暂停低通气综合征与胰岛β细胞功能障碍[J]. 国际呼吸杂志, 2011, 31(23): 1825-1828. DOI: 10.3760/cma.j.issn.1673-436X.2011.023.015 |
| |
| 作者姓名： | 卢巍 康健 |
| |
| 作者单位： | 中国医科大学附属第一医院呼吸科, 沈阳,110001 |
| |
| 摘 要： | 阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)是一种氧化应激性疾病,其特征性低氧方式-慢性间歇低氧诱导了机体氧化应激的产生,是累积多系统、多器官损害的病理生理基础.胰岛β细胞是最易受到氧化损伤和极易凋亡的细胞,氧化应激引起胰岛β细胞损伤是...
|
| 关 键 词： | 阻塞性睡眠呼吸暂停低通气综合征 慢性间歇低氧 氧化应激 胰岛β细胞功能 |
Obstructive sleep apnea-hypopnea syndrome and beta cell dysfunction |
| |
| LU Wei,KANG Jian. Obstructive sleep apnea-hypopnea syndrome and beta cell dysfunction[J]. International Journal of Respiration, 2011, 31(23): 1825-1828. DOI: 10.3760/cma.j.issn.1673-436X.2011.023.015 |
| |
| Authors: | LU Wei KANG Jian |
| |
| Abstract: | Obstructive sleep apnea-hypopnea syndrome (OSAHS) is characterized by chronic intermittent hypoxia (CIH),the oxidative stress induced by CIH can lead to multisystem and multi-organ injury.Pancreatic β cells are vulnerable to oxidative stress,for diabetes to develop,β-cell functional impairment induced by oxidative stress is needed.Intervention with antioxidant maybe a potential therapy for pancreatic injury in patients with OSAHS. |
| |
| Keywords: | Obstructive sleep apnea-hypopnea syndrome Chronic intermittent hypoxia Oxidative stress Pancreatic β cell dysfunction |
| 本文献已被 万方数据 等数据库收录！ |
