| 阿司匹林抵抗的机制 |
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| 引用本文： | 时芳芳,任传成. 阿司匹林抵抗的机制[J]. 国际脑血管病杂志, 2011, 19(11): 836-840. DOI: 10.3760/cma.j.issn.1673-4165.2011.11.007 |
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| 作者姓名： | 时芳芳 任传成 |
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| 作者单位： | 复旦大学附属上海市第五人民医院神经内科,上海,200240 |
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| 摘 要： | 近年来,阿司匹林抵抗现象越来越引起重视.研究人员已从多个方面对这种重要现象的机制进行了探索,包括患者依从性、实验室检测方法、阿司匹林剂量、遗传学、药物相互作用等;并提出了相应的管理方法,如提高患者依从性、避免药物相互作用、调整药物剂量、加用其他有潜在应用价值的抗血小板药等.文章对阿司匹林抵抗机制的研究进展进行了综述.
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| 关 键 词： | 阿司匹林 血小板聚集抑制药 抗药性 卒中 |
Mechanisms of aspirin resistance |
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| SHI Fang-fang,REN Chuan-cheng. Mechanisms of aspirin resistance[J]. International Journal of Cerebrovascular Diseases, 2011, 19(11): 836-840. DOI: 10.3760/cma.j.issn.1673-4165.2011.11.007 |
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| Authors: | SHI Fang-fang REN Chuan-cheng |
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| Abstract: | In recent years,more and more attention has been given to aspirin resistance.Researchers have explored the mechanisms of this important phenomenon from several aspects,including patient compliance,laboratory tests,aspirin dose,genetics,and drug interactions.Many appropriate management methods of aspirin resistance have been proposed,such as improving patient compliance,avoiding drug interactions,adjusting dose,and adding other antiplatelet drugs with potential application value.This article reviews the advances in research on the mechanisms of aspirin resistance. |
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| Keywords: | Aspirin Platelet aggregation inhibitors Drug resistance Stroke |
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