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| 腺苷及其受体参与外周痛觉信息调控的机制 | |
| 引用本文： | 赵静,米文丽,毛应启梁. 腺苷及其受体参与外周痛觉信息调控的机制[J]. 国际病理科学与临床杂志, 2011, 31(4): 301-304. DOI: 10.3969/j.issn.1673-2588.2011.04.006 |
| 作者姓名： | 赵静 米文丽 毛应启梁 |
| 作者单位： | 复旦大学上海医学院中西医结合系,上海,200032 |
| 摘 要： | 腺苷是一种遍布人体细胞的内源性核苷,通过其不同类型的受体(A1,A2A,A2B和A3受体)对机体的许多系统(特别是中枢神经系统)及组织发挥着重要的作用,参与调控睡眠、学习记忆、抑郁和焦虑等多种生理和病理过程.随着腺苷对受体亚型选择性激动剂和拮抗剂的开发,人们对腺苷及其受体在外周神经系统中的作用研究越来越深入,并逐步认识... |
| 关 键 词： | 腺苷 腺苷受体 外周痛觉信息调控 |
Mechanisms of adenosine and its receptors in pain modulation in the peripheral system |
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| ZHAO Jing,MI Wenli,MAO-YING Qiliang. Mechanisms of adenosine and its receptors in pain modulation in the peripheral system[J]. Journal of International Pathology and Clinical Medicine, 2011, 31(4): 301-304. DOI: 10.3969/j.issn.1673-2588.2011.04.006 | |
| Authors: | ZHAO Jing MI Wenli MAO-YING Qiliang |
| Affiliation: | ZHAO Jing1,MI Wenli1,MAO-YING Qiliang1,WANG Yanqing1,2(1.Department of Integrative Medicine and Neurobiology,Shanghai Medical College,2.Institutes of Brain Science,State Key Laboratory of Medical Neurobiology,Fudan University,Shanghai 200032,China) |
| Abstract: | Adenosine is an endogenous nucleoside that widely exists in the human body cells.Through activating different subgroups of adenosine receptors(A1,A2A,A2B,and A3 receptors),adenosine produces various effects in a broad spectrum of tissues,especially in the central nervous systems,which includes modulating physiological and pathological processes such as sleep,learning and memory,depression as well as anxiety.With the research development in the agonists and antagonists of adenosine receptors,the roles of ade... |
| Keywords: | adenosine adenosine receptors pain modulation in the peripheral system |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |