| 二阶导数光谱法测定酮洛芬体外经皮渗透量 |
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| 引用本文： | 胡晋红,朱宇,薛佩华. 二阶导数光谱法测定酮洛芬体外经皮渗透量[J]. 药学学报, 1997, 32(7): 542-545 |
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| 作者姓名： | 胡晋红 朱宇 薛佩华 |
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| 作者单位： | 长海医院药学部 |
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| 摘 要： | 为进一步探讨酮洛芬透皮给药的可行性,用二阶导数光谱法测定酮洛芬体外经皮渗透量。结果表明,本法可排除皮下组织的干扰,能准确测定药物体外渗透量,且操作简便、快速。平均回收率为99.00%±1.51%。
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| 关 键 词： | 二阶导数光谱法 酮洛芬 经皮渗透 |
| 收稿时间： | 1996-06-20 |
DETERMINATION OF PERMEATION OF KE |
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| JH Hu,Y Zhu and PH Xue. DETERMINATION OF PERMEATION OF KE[J]. Acta pharmaceutica Sinica, 1997, 32(7): 542-545 |
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| Authors: | JH Hu Y Zhu PH Xue |
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| Affiliation: | Department of Pharmacy, Changhai Hospital, Shanghai 200433. |
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| Abstract: | A second order derivative spectrophotometric method was developed for the permeative determination of ketoprofen in vitro. The method can avoid the disturbance of skin tissue. The procedure is simple and rapid. The results are accurate. The mean recovery of ketoprofen is 99.00% +/- 1.51%. |
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| Keywords: | Second order derivative spectrophotometry Ketoprofen Transdermal therapeutic system |
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