Unusual cases of neuronal intestinal dysplasia

Six children with isolated neuronal intestinal dysplasia (NID) and unusual complications are presented. Three had meconium peritonitis, one of them in association with a solid pyloric atresia, one midgut volvulus, one rectal stenosis, and one jejunojejunal intussusception. These cases show that patients with isolated NID may present with a heterologous pattern of symptoms very different from those generally reported, indicating that NID may not be a distinct clinical entity. The symptomatology of NID seems to be directly correlated with the degree of functional defect of gut motility. NID should be suspected in any case of functional small-bowel obstruction.Offprint requests to: P. Sacher