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| 白介素-18与急性冠状动脉综合征 | |
| 引用本文： | 胡章乐,马礼坤. 白介素-18与急性冠状动脉综合征[J]. 国际病理科学与临床杂志, 2007, 27(1): 14-59 |
| 作者姓名： | 胡章乐 马礼坤 |
| 作者单位： | 安徽省立医院心血管内科,合肥,230001 |
| 摘 要： | 动脉粥样硬化斑块的不稳定导致冠心病特殊疾病谱——急性冠状综合征的发生。炎症机制在动脉粥样硬化斑块的发生、发展中扮演重要角色。近年来，不断有研究证实前炎症因子白介素-18密切参与了此过程，并且与急性冠状动脉综合征的发生有着极强的关联。 |
| 关 键 词： | 白介素18 动脉粥样硬化 急性冠状动脉综合征 |
| 文章编号： | 1673-2588(2007)01-0057-03 |
| 收稿时间： | 2006-07-12 |
| 修稿时间： | 2006-07-12 |
Interleukin-18 and acute coronary syndrome |
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| HU Zhang-le,MA Li-kun. Interleukin-18 and acute coronary syndrome[J]. Journal of International Pathology and Clinical Medicine, 2007, 27(1): 14-59 | |
| Authors: | HU Zhang-le MA Li-kun |
| Affiliation: | Department of Cardiology, Anhui Provincial Hospital, Hefei 230001, China |
| Abstract: | As has been known to us, instability of atherosclerotic plaque leads to the development of clinical acute coronary syndrome. Inflammation has been proved to play an important role in the initiation and progression of atherosclerotic plaque. More recently, emerging study has confirmed this concept that the proinflammatory factor interleukin-18 is intimately involved in the above mentioned process and extremely associated with the development of the acute coronary syndrome. This article will review the relationship between interleukin-18 and acute coronary syndrome, and its prospect in clinical setting. |
| Keywords: | interleukin-18 atherosclerosis acute coronary syndrome |
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