近日节律的改变与高血压脑出血手术治疗预后关系的研究

目的：研究近日节律的改变与高血压脑出血手术治疗预后的关系。方法：收集100例高血压基底节区脑出血的病例，每例患者均进行了标准的开颅血肿清除术。术后连续24小时监测心率，每小时记录一次。用单一余弦法进行术后24小时心率的近日节律分析。根据术后近日节律的出现和消失将患者分组，利用统计学比较两组预后的差异。结果：术后24小时心率近日节律出现组预后好的患者比例明显优于消失组（P〈0．01）。结论：近日节律的改变有可能早期预测高血压脑出血手术治疗的预后。

Study of relationship between variation of circadian rhythm and postoperative prognosis from hypertensive intracerebral hemorrhage

Objective： Study of the relationship between change in circadian rhythm and postoperative prognosis from hypertensive intracerebral hemorrhage. Method： 100 cases of hypertensive intracerebral hemorrhage at basal ganglia had been collected, which ev- ery case was performed operation to remove hemotoma by standard craniotomy. Value of Heart Rate （HR） was recorded by monitor every 1 hour for 24 hours after operation. Circadian rhythm of the first 24-hour was analyzed by single Cosinor. 100 cases were divid- ed into two groups by appearance and disappearance of circadian rhythm after operation. The difference was compared by statistics.. Result： Percentage of good prognosis in appearance of circadian rhythm group was better than disappearance of circadian rhythm group （p〈~0. 01）. Conclusion： Change of circadian rhythm would be an early predictor of postoperative prognosis from hypertensive intracerebral hemorrhage.