| 木尘提取液诱发体外培养BALBA/c-3T3细胞微核和多核 |
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| 引用本文： | 何鹏, 吴德生, 董奇男. 木尘提取液诱发体外培养BALBA/c-3T3细胞微核和多核[J]. 中国公共卫生, 2000, 16(10): 896-897. DOI: 10.11847/zgggws2000-16-10-19 |
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| 作者姓名： | 何鹏 吴德生 董奇男 |
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| 作者单位： | 1.华西医科大学环境卫生学教研室, 成都610041 |
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| 基金项目： | 四川省卫生厅基金资助项目 |
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| 摘 要： | 为探讨木尘的诱变性,选择硬木和软木各一种,分别为榉木和桦木,制备成木尘水提取液和有机提取液,进行BALB/c-3T3细胞微核和多核诱导试验.结果显示榉木尘和桦木尘两种提取液均存在细胞毒性,并可引起BALB/c-3T3细胞微核和多核细胞率的明显升高,剂量反应关系成立.说明榉木尘和桦木尘两种提取液均具有诱变性.
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| 关 键 词： | 榉木 桦木 木尘 提取液 微核 多核 |
| 收稿时间： | 1999-12-03 |
| 修稿时间： | 1999-12-03 |
Frequencies of Micronucleated and Multinucleated Cells in BALB/c-3T3 Cells in Vitro Induced by Wood Dust Extracts. |
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| He Peng, . Frequencies of Micronucleated and Multinucleated Cells in BALB/c -3T3 Cells in Vitro Induced by Wood Dust Extracts.[J]. Chinese Journal of Public Health, 2000, 16(10): 896-897. DOI: 10.11847/zgggws2000-16-10-19 |
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| Authors: | He Peng) |
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| Affiliation: | 1.Dept. of environmental Hygiene, School of Public Health, West China University of Medical Sciences, Chengdu 610041 |
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| Abstract: | To study the mutagenicity of wood dust,BALB/c 3T3 cells were respectively treated with water's and organic extracts of beech wood dust and birch wood dust in vitro,and the frequencies of micronucleated and multinucleated cells in BALB/c 3T3 cells were observed.The results showed toxicity and the frequencies of micronucleated and multinucleated cells in BALB/c 3T3 cells were significantly increased by all extracts,and a dose response relationship was observed.It indicated both extracts of beech wood dust and birch wood dust were mutagenic. |
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| Keywords: | Beech Birch Wood dust Extracts Micronuclei |
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