血清T-PSA,F-PSA及F/T比值在前列腺癌和前列腺增生鉴别诊断中的意义

目的：探讨总前列前腺特异性抗原 （T-PSA）,游离前列腺特异性抗原（F-PSA）及F/T比值在前列腺癌（PCA）与前列腺增生（BPH）的鉴别诊断中的意义.方法 ：用电化学发光法测定70例PCA,100例BPH患者和100例正常体检组的T-PSA,F-PSA值并计算F/T比值.结果： PCA组,BPH组及正常体检组在T-PSA、F-PSA、F/T比值方面有显著性差异（P〈0.01）.当T-PSA在4.0～10.0ng/ml范围内,两组的T-PSA,F-PSA值均无显著性差异（P〉0.05）,F/T比值具有显著性差异（P〈0.01）.结论： T - PSA处于4.0～10.0 ng/ml时,同时检测T - PSA、F - PSA并计算F /T比值能更好的对PCA和BPH进行鉴别诊断.

Blood serum T-PSA,F-PSA and F/T ratio at prostate gland cancer and in prostate gland proliferation distinction diagnosis significance

Objective：Discusses in front of the total front row gland specificity antigen （T--PSA）,drifts away prostate gland specificity antigen （F --PSA） and the F/T ratio in prostate gland cancer （PCA） and in the prostate gland proliferation （BPH） distinction diagnosis significance. Methods： Uses electricity the chemiluminescence law to determine 70 example PCA, 100 the example BPH patient and 100 example normal physical examination group＇s T--PSA, F-- PSA value and calculates the FIT ratio. Results： The PCA group, the BPH group and the normal physical examination group in T--PSA,F--PSA,the F/T ratio aspect have the significance difference （P〈0.01）. When T--PSA in the 4.0-10.0ng/ml scope,two group of T--PSA, F--PSA values does not have the significance difference （P〉0.05）, F/T ratio to have the significance difference （P〈0.01）. Conclusion： T -- PSA is in 4.0-10. When 0 ng/ml,simultaneously examines T -- PSA,F -- PSA and calculates the F/T ratio to be able better carries on the distinction diagnosis to PCA and BPH.