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| 氨酚曲马多片的镇痛作用 | |
| 引用本文： | 刘广军. 氨酚曲马多片的镇痛作用[J]. 中国新药杂志, 2006, 15(23): 2079-2081 |
| 作者姓名： | 刘广军 |
| 作者单位： | 常州市第二人民医院,常州,213003 |
| 摘 要： | 氨酚曲马多片（及通安）是一种新型镇痛药，为曲马多37．5mg和对乙酰氨基酚325mg组成的复方制剂。它能通过多种途径抑制疼痛，广泛用于中度疼痛的治疗。其镇痛效果优于单独使用两种单组分镇痛药物的效果，同时由于该复方制剂中每种药物成分的给药剂量较单独使用时低，从而减少了不良反应。现对其药效学、药动学、临床应用及不良反应做一介绍。 |
| 关 键 词： | 氨酚曲马多 曲马多/对乙酰氨基酚 镇痛药 |
| 文章编号： | 1003-3734（2006）23-2079-03 |
| 收稿时间： | 2006-06-23 |
| 修稿时间： | 2006-06-23 |
Analgesic activity of compound paracetamol and tramadol hydrochloride tablets |
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| LIU Guang-jun. Analgesic activity of compound paracetamol and tramadol hydrochloride tablets[J]. Chinese Journal of New Drugs, 2006, 15(23): 2079-2081 | |
| Authors: | LIU Guang-jun |
| Abstract: | The compound paracetamol (325 mg) and tramadol hydrochloride (37.5 mg) tablets relieve moderate pains by manifold pathways. The compound paracetamol and tramadol provides more superior analgesic efficacy than monotherapy of either agent, and showed less adverse reactions due to reduced doses of each component in the compound regimen compared to individual dose in monotherapy of each agent. This review presents the pharmacokinetics,pharmacodynamics,pharmacotherapeutics and safety of the compound paracetamol and tramadol. |
| Keywords: | paracetamol and tramadol hydrochloride tablets tramadol/ paracetamol analgesics |
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| 点击此处可从《中国新药杂志》浏览原始摘要信息 | |