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| ADC值鉴别甲状腺结节的良恶性 | |
| 引用本文： | 闫斌,刘红娟,王春宝,李敏,闵志刚,麻少辉,范妤欣,张明.ADC值鉴别甲状腺结节的良恶性[J].中国医学影像技术,2011,27(3):510-514. |
| 作者姓名： | 闫斌 刘红娟 王春宝 李敏 闵志刚 麻少辉 范妤欣 张明 |
| 作者单位： | 1. 西安交通大学医学院第一附属医院影像科,陕西,西安,710061 2. 西安交通大学医学院第一附属医院ICU,陕西,西安,710061 3. 西安交通大学医学院第一附属医院病理科,陕西,西安,710061 |
| 基金项目： | 西安交通大学医学院光华创新基金(0203127)。 |
| 摘 要： | 目的 探讨MR DWI的ADC值鉴别诊断甲状腺良恶性结节的价值。方法 回顾性分析27例(40个病灶)经病理证实的甲状腺结节患者资料,术前均接受常规MR、脂肪抑制增强扫描明确病变实性部分;单次激发自旋平面回波成像(SS SE-EPI)DWI扫描(b值取0、500 s/mm2),测量实性部分的平均ADC值。依据病理结果将结节分为良性组及恶性组,比较其ADC值差异,绘制ROC曲线,确定诊断阈值,评价筛检效能。结果 40个结节中,甲状腺恶性结节15个,平均ADC值为(1.22±0.27)×10－3 mm2/s,95%可信区间(1.07~1.37)×10－3 mm2/s;良性结节25个,平均ADC值为(2.20±0.40)×10－3 mm2/s,95%可信区间(2.04~2.37)×10－3 mm2/s。恶性组平均ADC值显著低于良性组(P＜0.05)。ROC曲线下面积为0.98、诊断阈值1.49×10－3 mm2/s时,诊断敏感度为86.70%,特异度为100%,准确率为95.00%。结论 甲状腺良恶性结节的ADC值显著不同,MR DWI可鉴别甲状腺结节的良恶性。 |
| 关 键 词： | 甲状腺结节 甲状腺疾病 扩散磁共振成像 |
| 收稿时间： | 2010/7/21 0:00:00 |
| 修稿时间： | 2010/11/26 0:00:00 |
ADC values in differentiation of benign and malignant thyroid nodules |
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| YAN Bin,LIU Hong-juan,WANG Chun-bao,LI Min,MIN Zhi-gang,MA Shao-hui,FAN Yu-xin and ZHANG Ming.ADC values in differentiation of benign and malignant thyroid nodules[J].Chinese Journal of Medical Imaging Technology,2011,27(3):510-514. | |
| Authors: | YAN Bin LIU Hong-juan WANG Chun-bao LI Min MIN Zhi-gang MA Shao-hui FAN Yu-xin and ZHANG Ming |
| Institution: | Department of Radiology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an 710061, China;ICU, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Pathology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Radiology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Radiology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Radiology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Radiology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Radiology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an 710061, China |
| Abstract: | Objective To assess the application of ADC value in differentiating benign and malignant thyroid nodules with MR DWI.Methods The ADC values of 40 thyroid nodules from 27 patients confirmed pathologically were analyzed retrospectively.Routine MR T1W,T2W and contrast enhanced fat suppression scan were performed to confirm the solidity of thyroid nodules.DWI were acquired using single shot spin echo-planner imaging(SS SE-EPI) sequence with diffusion-sensitizing gradients using b factors of 0 and 500 s/mm2.Thyr... |
| Keywords: | Thyroid nodule Thyroid diseases Diffusion magnetic resonance imaging |
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