Antitumor agents, 115. Seselidiol, a new cytotoxic polyacetylene from Seseli mairei |
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| Authors: | C Q Hu J J Chang K H Lee |
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| Affiliation: | Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina, Chapel Hill 27599. |
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| Abstract: | ![]()
Seselidiol [1], a new polyacetylene, has been isolated from the roots of Seseli mairei. On the basis of chemical and spectroscopic evidence, its structure has been established as heptadeca-1,8(Z)-diene-4,6-diyne-3,10-diol. Seselidiol and its acetate have been demonstrated to show moderate cytotoxicity against KB, P-388, and L-1210 tumor cells. |
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