胰腺腺鳞癌的CT诊断(附3例报道及文献综述)

目的 探讨胰腺腺鳞癌的影像、病理及肿瘤生物学行为的特点,以期提高对本病的认识,进而尽早做出正确诊断,制定恰当、合理治疗措施,改善患者的预后.资料与方法 回顾性分析、总结经病理证实的3例胰腺腺鳞癌患者的影像学资料、相关实验室检查、治疗方法及预后.结果 1例表现为中央明显坏死、液化的胰头肿瘤,另2例表现呈浸润性生长、早期出现转移.镜下肿瘤呈现腺癌和鳞癌的形态特点,免疫组织化学提示肿瘤含有腺癌和鳞癌成分.术后患者生存3～11个月,均死于肿瘤复发和肝转移.结论 肿瘤中央出现明显坏死、液化,或呈浸润性生长、早期出现转移是胰腺腺鳞癌的特点.

CT Features of Adenosquamous Carcinoma of Pancreas: Three Cases Report and Literature Review

Objective Adenosquamous carcinoma(ASC) of pancreas is rare malignant tumor and difficult to diagnose correctly before operation.We investigated the radiologic findings of ASC and reviewed the relative literatures to elucidate this rare disease.Materials and Methods Three patients(2 females,1 male,age ranged from 38-73y) with ASC of pancrease who underwent surgical treatment at our hospital between April 2006 and April 2008 were retrospectively reviewed.Results 1 patient exhibited a large central cystic lesion with heterogeneous enhancement in the head of pancrease.The other patients showed poor defined pancreatic mass with early adjacent metastasis.Microscopic findings indicated both adenocarcinoma and squamous component presented in all the lesions.Postoperative survival time ranged from 3-11 months.Conclusion Central cystic lesion with heterogeneous enhancement in pancrease,pancreatic mass with early adjacent metastasis are important features to diagnose ASC.