精神心理干预在功能性消化不良的药物治疗中的作用

目的：探讨功能性消化不良（FD）药物治疗与精神心理干预的临床疗效。方法：将348例FD门诊病人随机分为对照组和心理干预组各174例，对照组为单纯药物治疗组[兰索拉唑、莫沙必利、地西泮或氟哌噻吨／美利曲辛（黛力新）]；心理干预组在药物治疗的基础上采用精神心理疏导（启发开导和精神支持）及生活指导（生活饮食习惯），观察其疗效。结呆：对照组中显效60例（34．5％），有效72例（41．4％），总有效率75．9％；心理干预组中显效114例（65．5％），有效48例（27．6％），总有效率93．1％，两组总有效率差异具有显著性（P〈0．05）。结论：在抑酸药、促胃动力药及抗焦虑抑郁药治疗FD病人的基础上，加以精神心理疏导及生活指导能取得更好的治疗效果。

The effect of psychotherapy intervention on pharmacotherapy of patients with functional dyspepsia

Objective： To investigate the clinical effect of the medicinal treatment and psychotherapy intervention on patients with functional dyspepsia （FD）. Methods： Three hundred and forty-eight outpatients with FD were randomly divided into the control group and psychotherapy intervention group, with 174 cases in each group. The control group was given medicinal treatment alone such as lansoprazole, mosapride, diazepam or flupentixol ＋ melitracen （Deanxit）. The psychotherapy intervention group received psychological intervention （inspiring enlightenment and spirit support） and life instruction （the habit of living and diet） in addition to the medication. The curative effect was observed. Results： In the control group, 60 cases （34.5%） had excellent efficacy and 72 cases （41.4%） were effectively cured, therefore the total effective rate was 75.9%. While in the psychotherapy intervention group, 114 cases （65.5%） were excellent, 48 cases （27.6%） were effective, therefore the total effective rate was 93.1%. The difference of the total effective rate between the two groups was notable （P〈0.05）. Conclusion： In addition to antiacid drugs, prokinetic agents, anti-anxiety agents and antidepressive agents, combined psychological intervention and living instruction have certain curative effect on the FD sufferers.