非肝硬化食管胃底静脉曲张性上消化道出血患者内镜检查时长的相关影响因素

目的 探讨非肝硬化食管胃底静脉曲张性上消化道出血患者内镜检查时长的相关影响因素.方法 回顾性分析在合肥市第三人民医院行内镜检查的198例非肝硬化食管胃底静脉曲张性上消化道出血患者的临床资料,按检查的时间分为24 h内内镜检查者(及时内镜检测组)125例和24 h以外行内镜检查者(拖延内镜检测组)73例,比较两组患者的性别、年龄、平均动脉收缩压、平均动脉舒张压、并发症、病变部位、血红蛋白浓度,将单因素分析中差异有统计学意义的变量纳入Logistic回归分析,以确定行内镜检查时间的独立影响因素,并比较两组患者在研究期间的生存率.结果 性别、年龄、血红蛋白浓度、是否合并并发症以及病变部位是非肝硬化食管胃底静脉曲张性上消化道出血患者行内镜检查时长相关影响因素(P<0.05);经多因素Logistic回归分析结果显示,年龄、是否合并并发症、血红蛋白浓度以及病变部位均为非肝硬化食管胃底静脉曲张性上消化道出血患者行内镜检查时长的独立影响因素(P<0.05);及时内镜检查组患者的1年生存率为99.2％,拖延内镜检查组1年生存率为94.5％,两组患者1年生存率比较差异具有统计学意义(P<0.05).结论 年龄、是否合并并发症、血红蛋白浓度以及病变部位均为非肝硬化食管胃底静脉曲张性上消化道出血患者行内镜检查时长的独立影响因素,对于合并危险因素的患者要给予及时合理的干预,避免临床不良事件的发生,提高患者的生存率.

Related factors of endoscopic examination time in upper gastrointestinal bleeding in patients with non-liver cirrhosis with esophageal and gastric varices

Objective To investigate the related factors of endoscopic examination time in upper gastrointesti-nal bleeding in patients with non-liver cirrhosis with esophageal and gastric varices. Methods The clinical data of 198 patients with gastrointestinal bleeding and non-cirrhotic esophageal varices undergoing endoscopy was retrospectively analyzed. These patients were divided into the prompt endoscopy group (within 24 h, n=125) and the delayed endoscopy group (without 24 h, n=73) according to examination time. The gender, age, average systolic pressure, mean diastolic ar-terial pressure, complications, pathological change, hemoglobin concentration of the two groups were compared. The dif-ferences with statistical analysis were included in logistic regression analysis to determine the independent influencing factors of endoscopic examination time, and the survival rates of the two groups were compared during the study period. Results The sex, age, hemoglobin concentration, whether complications and location of lesion were the related factors of endoscopic examination time in upper gastrointestinal bleeding in patients with non-liver cirrhosis with esophageal and gastric varices (P<0.05). Multivariate logistic regression analysis showed that, age, hemoglobin concentration, whether with complications and location of lesion were the independent factors of endoscopic examination time in up-per gastrointestinal bleeding in patients with non-liver cirrhosis with esophageal and gastric varices (P<0.05). The surviv-al rate of the prompt endoscopy group in one year was 99.2％which was significantly higher than 94.5％of the delayed endoscopy group (P<0.05). Conclusion The age, hemoglobin concentration, whether with complications and location of lesion were the independent factors of endoscopic examination time in upper gastrointestinal bleeding in patients with non-liver cirrhosis with esophageal and gastric varices. For the patients with the risk factors should be given timely and reasonable intervention, to avoid adverse clinical events, and improve the survival rate of patients.