| 结核分枝杆菌耐利福平机制及其研究进展 |
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| 引用本文： | 向敏. 结核分枝杆菌耐利福平机制及其研究进展[J]. 海南医学, 2017, 28(17). DOI: 10.3969/j.issn.1003-6350.2017.17.031 |
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| 作者姓名： | 向敏 |
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| 作者单位： | 遵义医学院附属医院呼吸二科,贵州 遵义,563003 |
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| 摘 要： | 结核病是严重危害公众健康的全球性公共卫生问题,耐药结核病尤其是耐多药结核病的传播使结核病疫情更加严峻.利福平是重要的一线抗结核药之一,并且作为耐多药结核病的替代标志物.因此了解结核分枝杆菌耐利福平机制对预防及控制耐药结核病有着重要意义.本文就结核分枝杆菌耐利福平机制及其研究进展进行综述.
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| 关 键 词： | 结核分枝杆菌 利福平 耐药 机制 |
Mechanism of rifampicin resistance in Mycobacterium tuberculosis and its research progress |
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| XIANG Min. Mechanism of rifampicin resistance in Mycobacterium tuberculosis and its research progress[J]. Hainan Medical Journal, 2017, 28(17). DOI: 10.3969/j.issn.1003-6350.2017.17.031 |
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| Authors: | XIANG Min |
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| Abstract: | Tuberculosis is a global public health problem that seriously endanger public health, and the spread of drug-resistant tuberculosis, especially multidrug-resistant tuberculosis (MDR-TB), makes tuberculosis more severe. Rifampicin is one of the important first-line anti-tuberculosis drugs and serves as an alternative marker for MDR-TB. Therefore, understanding the mechanism of rifampicin resistance in Mycobacterium tuberculosis is of great significance to the prevention and control of drug-resistant tuberculosis. In this paper, the mechanism of rifampicin resistance in Myco-bacterium tuberculosis and its research progress is reviewed. |
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| Keywords: | Mycobacterium tuberculosis Rifampicin Drug resistance Mechanism |
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