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DEC1 nuclear expression: a marker of differentiation grade in hepatocellular carcinoma |
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| Authors: | Shi Xiao-Hong Zheng Yan Sun Qing Cui Jing Liu Qing-Hua Qü Fei Wang Yun-Shan |
| Affiliation: | Xiao-Hong Shi,Department of Laboratory Medicine,Shandong Provincial Qianfoshan Hospital,Shandong University,Jinan 250014,Shandong Province,China Yan Zheng,Yun-Shan Wang,Shandong Province Key Lab of Tumor Target Molecule,Jinan Central Hospital Affiliated to Shandong University,Jinan 250013,Central Laboratory,China Qing Sun,Jing Cui,Department of Pathology,Shandong Prov... |
| Abstract: | AIM: To investigate the expression patterns of human differentiated embryo chondrocyte 1 (DEC1) in hepatocellular carcinoma (HCC) and corresponding adjacent non-tumor and the normal liver tissues, the association between DEC1 expression and histopathological variables and the role of DEC1 in hepatocarcinogenesis. METHODS: The expression of DEC1 was detected immunohistochemically in 176 paraffin-embedded sections from 63 patients with HCC and 50 subjects with normal liver tissues. RESULTS: DEC1 protein was p... |
| Keywords: | Differentiated embryo chondrocyte 1 Hepatocellular carcinoma Differentiation Immunohistochemistry |
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