147例药品不良反应报告分析

目的：了解我院药物不良反应（ADR）发生的特点，促进临床合理用药。方法：对我院2005年1月～2007年10月收集的147例ADR报告从年龄分布、药品种类、给药途径、累及器官或系统和临床表现等方面进行统计分析。结果：147例ADR报告中，药物以抗茵药物居多（占52．38％）。≥60岁的老年患者居高（占46．94％）。静脉给药是引起ADR的主要给药方式（占55．10％）。ADR的主要临床表现以皮肤损害为主（占51.02％）。结论：合理用药，减少ADR的发生。

Analysis of 147 ADR Reports in Our Hospital

Objective： To investigate the characteristics of adverse drug reactions （ADR） in our hospital to promote clinical rational drug use. Method： 147 ADR cases collected from Jan. 2005 to Oct. 2007 in our hospital were analyzed in respect of age distribution, drug species, routes of administration, organs or systems involved and clinical manifestations. Result： In the 147 ADR cases,52.38% were induced by antibacterial, 46.94% occurred in patients aged ≥60a, 55.10% were induced intravenously, and the damages of skin were the most common manifestations. Conclusion： Rational use of drugs should be emphasized to decrease the occurrence of ADR.