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| 赣皖乌头生物碱的研究——Ⅰ.赣皖乌头中生物碱的分离与鉴定 | |
| 引用本文： | 陈葆仁,杨义芳,田如美,张长盘,萧幼静,刘铭勋. 赣皖乌头生物碱的研究——Ⅰ.赣皖乌头中生物碱的分离与鉴定[J]. 药学学报, 1981, 16(1): 70-72 |
| 作者姓名： | 陈葆仁 杨义芳 田如美 张长盘 萧幼静 刘铭勋 |
| 作者单位： | 江西医学院(陈葆仁，田如美，张长盘)，赣州地区药检所(杨义芳)，兴国县卫生局(萧幼静)，江西医学院(刘铭勋) |
| 摘 要： | 赣皖乌头(Aconitum finetianum Hand-Mazz.)系毛茛科乌头属植物,俗称“破叶莲”、“鸡脑王”。为多年生草本,江西省兴国县有栽培及野生植物。民间广泛用于治疗菌痢、肠炎、毒蛇咬伤、无名肿毒。其根含有丰富的生物碱,但其成分迄今未见报告。 |
| 收稿时间： | 1980-02-29 |
ALKALOIDS OF ACONITUM FINETIANUM HAND-MAZZⅠ. ISOLATION AND IDENTICATION OF ALKALOIDS FROM ACONITUM FINETIANUM HAND-MAZZ |
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| Chen Baoren,Yang Yifang,Tian Rumei,Zhang Ghangpan,Xiao Youzing and Liu Mingxun. ALKALOIDS OF ACONITUM FINETIANUM HAND-MAZZⅠ. ISOLATION AND IDENTICATION OF ALKALOIDS FROM ACONITUM FINETIANUM HAND-MAZZ[J]. Acta pharmaceutica Sinica, 1981, 16(1): 70-72 | |
| Authors: | Chen Baoren Yang Yifang Tian Rumei Zhang Ghangpan Xiao Youzing Liu Mingxun |
| Abstract: | Five alkaloids were isolated from the roots of Aconitum finetianum (Hand-Mazz.) by a combination of pH extraction and chromatographic techniques. Chemical and spectral studies suggested that they are a series of the lycoctonine-type alkaloid. Three of them were identified as delsoline, avadharidine and lycoctonine, by comparing their physical properties with known compounds. The formulas of two others alkaloids are designated as C27H21N3O5(141～142℃) and C22H31NO3 (221～226℃). Their structures are under investigation. Delsoline is useful for acute dysentery, acute enteritis and a relaxant of the smooth muscle of intestines. |
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