21d头低位卧床过程中套带对抗心血管脱适应的作用

目的在２１ ｄ 头低位卧床的１ ～１０ ｄ 使用套带，能明显阻止立位耐力下降，在后续卧床中观察套带组不使用套带时的心血管脱适应变化，以进一步验证套带的防护效果。方法 套带组继卧床第１ ～１０ 天使用套带后、卧床第１１ ～１７ 天不使用套带，最后４ ｄ 再使用套带。在卧床第１７ 、２１ 天时进行正立位７５°耐力检查。结果套带组５ 人（ 卧床第１０ 天时都通过２０ ｍｉｎ 立位） 停用套带１ ｗｋ ，５ 人中有２ 人未通过２０ ｍｉｎ 立位，一名１７ ｍｉｎ 出现晕厥前症状，另一名４ ｍｉｎ 出现晕厥。再用套带４ｄ ，套带组５ 人又全部通过２０ ｍｉｎ 立位。结论（１） 停止使用持续加压套带引起了心血管脱适应，（２）卧床后期四肢使用持续加压套带４ ｄ 能有效阻止立位耐力下降。

Effect of Extremity Cuffs as a Countermeasure against the Cardiovascular Deconditioning during 21 d Head-down Bedrest

Objective To affirm the protective effect of inflated cuffs. Method The protective effect against the cardiovascular deconditioning of inflated cuffs on the upper parts of thighs and arms during the 1 st through 10 th days of 21 d bedrest has been reported previously.The effect of the cuffs during the rest of the 21 d bedrest were studied in this paper.Five subjects in cuffs group whose orthostatic tolerance were well maintained continued bed rest for 7 d without inflated cuffs. For the last 4 days of this period, inflated cuffs were again applied. Orthostatic tolerance of subjects in cuffs group with and without cuffs were measured. Result Two of the five subjects suffered orthostatic intolerance on the 17th day. No sign of orthostatic intolerance were observed by the end of bedrest. Conclusion (1) the cardiovascular deconditioning developed when inflated cuffs were not used, and (2) the use of inflated cuffs for 4 d improves the orthostatic tolerance.