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| 调神方对老年性痴呆大鼠学习记忆和细胞因子调节的实验研究 | |
| 引用本文： | 王健,尹兆宝,林水淼. 调神方对老年性痴呆大鼠学习记忆和细胞因子调节的实验研究[J]. 中国组织工程研究与临床康复, 2002, 6(7): 964-965 |
| 作者姓名： | 王健 尹兆宝 林水淼 |
| 作者单位： | 上海中医药大学老年医学研究所,上海,200032 |
| 摘 要： | 目的探讨调神方对老年性痴呆(AD)大鼠学习记忆和细胞因子调节的作用机制。方法建立AD鼠模型,分为正常组、衰老组、假损伤组、模型组、调神方组、他克林组,观察Y-电迷宫和血清细胞因子。结果调神方能明显提高Y-电迷宫正确次数,明显下调血清白介素-1β(IL-1β)、白介素-6(IL-6)的水平。结论调神方可能通过调整AD大鼠的免疫状态而提高学习记忆能力。 |
| 关 键 词： | 调神方 老年性痴呆大鼠 学习记忆 细胞因子 |
| 文章编号： | 1671-5926(2002)07-0964-02 |
| 修稿时间： | 2001-12-25 |
Experimental study of " Vitality-regulation Recipe" on the learning and memory impairment and cell factor in the rat with Alzheimer dementia |
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| WANG Jian,YIN Zhao bao,LIN Shui miao. Experimental study of " Vitality-regulation Recipe" on the learning and memory impairment and cell factor in the rat with Alzheimer dementia[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(7): 964-965 | |
| Authors: | WANG Jian YIN Zhao bao LIN Shui miao |
| Affiliation: | WANG Jian,YIN Zhao bao,LIN Shui miao.Institute of Geriatrics,Shanghai University of Traditional Chinese Medication,Shanghai 200032,China |
| Abstract: | Objective To study the mechanism of the Vitality regulation Recipe(VRR) on the learning and memory impairment and cell factor in the rat with Alzheimer dementia.Methods The experimental rat models with Alzheimer dementia were divided into the control group,senility group,pseudo injuried group,model group.VRR group and mcrine group.These groups were observed by the methods of Y electrical maze,and serum cell factor.Results VRR could remarkably increased rightly rate of Y electrical maze,and descend IL 1,IL 6 level of serum.Conclusion VRR could improve funcion of cognition by regulating immunity state of the rat with Alzheimer dementia. |
| Keywords: | Vitality regulation Recipe the rat with Alzheimer dementia learning and memory cell factor |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |