| 体重超重对多囊卵巢综合征患者内分泌改变的影响 |
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| 引用本文： | 李琳,杨冬梓,冯淑英. 体重超重对多囊卵巢综合征患者内分泌改变的影响[J]. 实用妇产科杂志, 2005, 21(9): 538-540 |
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| 作者姓名： | 李琳 杨冬梓 冯淑英 |
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| 作者单位： | 中山大学附属第二医院,广东,广州,510120 |
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| 摘 要： | 目的:探讨体重超重对多囊卵巢综合征患者的内分泌改变的影响。方法:检测31例体重超重和102例非超重多囊卵巢综合征患者的内分泌激素和胰岛素敏感性。结果:超重组的雄激素和空腹胰岛素水平显著升高(P<0.05,P<0.01),GIR显著下降(P<0.01),HOMAIR明显升高(P<0.01),超重组胰岛素抵抗的发生率明显高于非超重组,BMI与胰岛素敏感性呈负相关。结论:体重超重的PCOS患者高雄激素血症和胰岛素抵抗都更为严重,对超重PCOS患者的治疗应注重于纠正高雄激素血症和胰岛素抵抗状态。
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| 关 键 词： | 多囊卵巢综合征 超重 胰岛素抵抗 高雄激素血症 |
| 文章编号： | 1003-6946(2005)09-538-03 |
| 修稿时间： | 2005-06-26 |
Impact of Overweight on the Endocrine Changes in PCOS Patients |
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| LI Lin,YANG Dongzi,FENG Shuying. Impact of Overweight on the Endocrine Changes in PCOS Patients[J]. Journal of Practical Obstetrics and Gynecology, 2005, 21(9): 538-540 |
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| Authors: | LI Lin YANG Dongzi FENG Shuying |
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| Abstract: | Objective: To explore the impact of overweight on the endocrine changes in PCOS patients. Methods: The hormone level and insulin sensitivity were detected in 31 overweight and 102 non-overweight PCOS patients.Results: The serum androgen and fasting insulin levels were significantly higher in overweight group with lower GIR and higher HOMA-IR, when compared to non-overweight group (P<0.05,P<0.01). The incidence of insulin resistance was higher in overweight group than non-overweight group. BMI was negatively related to insulin sensitivity. Conclusions: Hyperandrogenism and insulin resistance were more obvious in overweight PCOS patients, which should be emphasized in their treatment. |
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| Keywords: | Polycystic ovarian syndrome Overweight Insulin resistance Hyperandrogenism |
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