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蒲黄解毒汤治疗急性胃粘膜病变的临床应用及实验研究
引用本文:王长洪,周莹,王艳红,樊新亚,陈山泉,高学武,宋同恺,侯晓娜.蒲黄解毒汤治疗急性胃粘膜病变的临床应用及实验研究[J].中国中西医结合消化杂志,1995(2).
作者姓名:王长洪  周莹  王艳红  樊新亚  陈山泉  高学武  宋同恺  侯晓娜
作者单位:沈阳军区总医院
摘    要:以中药蒲责解毒汤和西药西咪替丁(对照组)对比治疗急性胃粘膜病变(AGML)91例,疗程4周,并进行了4~24个月的内镜随访观察。中药组盯例,治愈51例,好转4例,无变化1例,演变为隆起型5例;对照组30例,治愈19例,好转4例,无变化3例,演变为隆起型4例。并通过对患者的幽门螺杆菌(HP)的检测表明,蒲黄解毒汤对HP有抑制作用。动物实验表明该药对吲哚美辛、利血平所致的大鼠急性胃粘膜损伤有明显保护作用.

关 键 词:蒲黄解毒汤,西咪替丁,急性胃粘膜病变,幽门螺杆菌

The clinical contrast and laboratory study on treating AGML with Puhuangjiedu decoction and cimetidine
Wang Changhong,Zhou Ying,Wang Yanhong et alGeneral Hospital of Shenyang Command PLA.The clinical contrast and laboratory study on treating AGML with Puhuangjiedu decoction and cimetidine[J].Chinese Journal of Integrated Traditional and Western Medicine on Digestion,1995(2).
Authors:Wang Changhong  Zhou Ying  Wang Yanhong General Hospital of Shenyang Command PLA
Abstract:91 cases of patient with acute gastric mucosal lesion (AGML) proved by gastroscopy were diviced into two groups Puhuangjiedu decoction (61 cases)and cimetidine (30 cases)groups. 4-week course and 4-24 month follow-up by gastroscopy were performed. 51 cases of healing, 4 cases of reversion,1 case of nonchange and 5 cases of convex type were foumd in Puhuangjiedu decoction group. But, 19 cases of healing, 4 cases of reversion, 3 cases of nonchange and 4 cases of convex type were found in cimetidine group. Chinese medicine is superior to cimetidine and can control HP and protect the acute gastric munosa damage of rates induced by reserpineand indomethacin.
Keywords:Puhangjiedu decoction  Cimetidine  Acute gastric mucosal lesion
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