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脑膜转移瘤临床特征及脑脊液细胞学分析
引用本文:刘青蕊,韩颖,梅风君,段宏伟,李凤銮,赵静霞.脑膜转移瘤临床特征及脑脊液细胞学分析[J].脑与神经疾病杂志,2010,18(2):143-145.
作者姓名:刘青蕊  韩颖  梅风君  段宏伟  李凤銮  赵静霞
作者单位:河北医科大学第四医院神经内科,石家庄,050011
摘    要:目的探讨脑膜转移瘤的早期临床特点和脑脊液细胞学特征。方法对79例脑膜转移瘤患者的原发病、临床特点、脑MRI和脑脊液细胞学变化进行回顾性分析。结果79例患者中以原发于肺癌及乳腺癌多见,分别为肺癌30例(37.98%)、乳腺癌18例(22.79%)。早期多出现剧烈头痛(71例,89.87%)和脑膜刺激征(69例,87.34%)。MRI强化检查,52例(69.33%)出现脑膜增厚、结节强化。51例行脑脊液检查,颅内压均有不同程度增高,细胞学分析显示,出现异型细胞和肿瘤细胞30例(58.82%)。结论脑膜转移瘤患者早期多出现剧烈头痛和脑膜刺激征,MRI增强检查可明显提高其早期诊断率。脑脊液细胞学可为诊断提供确诊依据。

关 键 词:脑膜转移瘤  早期临床特征  强化磁共振成像  脑脊液细胞学

The analysis of clinical features and CSF cytology in patients with meningeal metastasis
LIU Qing-rui,HAN Ying,MEI Feng-jun,DUAN Hong-wei,LI Feng-luan,ZHAO Jing-xia.The analysis of clinical features and CSF cytology in patients with meningeal metastasis[J].Journal of Brain and Nervous Diseases,2010,18(2):143-145.
Authors:LIU Qing-rui  HAN Ying  MEI Feng-jun  DUAN Hong-wei  LI Feng-luan  ZHAO Jing-xia
Institution:LIU Qing-rui,HAN Ying,MEI Feng-jun,DUAN Hong-wei,LI Feng-luan,ZHAO Jing-xia.Department of Neurology,the Fourth Hospital of Hebei Medical University.Shijiazhuang 050011,China
Abstract:Objective To explore early clinical characteristics and features of cerebrospinal fluid(CSF)cytology in patients with meningeal metastasis(MM).Methods Seventy-nine patients with MM were retrospectively studied in primary cancer,clinical characteristics,brain MRI and the changes of cerebrospinal fluid cytology.Results The most common tumor was lung cancer(37.98%),followed by breast(22.79%)in the 79 patients;Mostly there were severe headache(71 cases,89.87 %)and meningeal irritation signs(69 cases,87.34%);52 ...
Keywords:Meningeal metastasis  Early clinical features  Enhancement magnetic resonance imaging  CSF cytology  
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