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噬血细胞综合征发病机制及实验室诊断的研究进展
引用本文:朱松山,殷君,梁庆华,黄金. 噬血细胞综合征发病机制及实验室诊断的研究进展[J]. 现代检验医学杂志, 2013, 0(6): 41-43
作者姓名:朱松山  殷君  梁庆华  黄金
作者单位:[1]广西壮族自治区江滨医院检验科,南宁530021 [2]广西中医药大学第一附属医院检验科,南宁530023
摘    要:噬血细胞综合征(hemophagocyticsyndromes,HPS)是由于机体免疫系统功能紊乱,导致NK细胞和淋巴细胞的异常活化、大量细胞因子的释放,引起了组织细胞等吞噬细胞功能过度旺盛,从而出现吞噬大量正常造血细胞的现象。HPS病情凶险,发展迅速,临床及实验室检查表现多样,该文就近年来国内外对该病的病因、机制、临床表现、实验室诊断等研究进展做一综述。

关 键 词:噬血细胞综合征  发病机制  实验室诊断

Research on the Progress of Pathogenesis and Laboratory Diagnosis of Hemophagocytic Syndromes
ZHU Song-shan,YIN Jun,LIANG Qing-hua,HUANG Jin. Research on the Progress of Pathogenesis and Laboratory Diagnosis of Hemophagocytic Syndromes[J]. Journal of Modern Laboratory Medicine, 2013, 0(6): 41-43
Authors:ZHU Song-shan  YIN Jun  LIANG Qing-hua  HUANG Jin
Affiliation:1 (1. Department of Clinical Laboratory,the J iangbin Hospital of Guangxi , Nanning 530021,Chinas2. Department of Clinical Laboratory, the First Affiliated Hospital of Guangxi Chinese Medicine University ,Nanning 530023 ,China)
Abstract:Hemophagocytic syndromes (HPS) is a phenomenon of normal hematopoietic ceils phagocytosis due to the body's immune system dysfunction,leading to abnormal activation of NK cells and lymphocytes,a large number of the release of cy- tokines, cause the tissue cells,such as phagocytes function excessively strong. HPS is a dangerous illness that rapid development, diversity of clinical manifestations and laboratory examination. This summarize review the etiology, mechanism, clinical manifestation,laboratory diagnosis of the HPS in the recent years internal and abroad.
Keywords:hemophagocytic syndromes(HPS)  pathogenesis  laboratory diagnosis
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