生脉饮加味治疗鼻咽癌放疗时涎腺受损的临床研究

目的：探讨应用生脉饮加味方剂治疗鼻咽癌放疗时唾液腺受损的临床疗效。方法：将96例首次根治性放射性治疗的鼻咽癌患者随机分为实验组（放疗加药物）和对照组（单纯放疗）,每组48例,放疗总剂量DT60～70Gy,6～7周,常规分割,放射野均包括面颈联合野。唾液腺受损程度通过视觉模拟评分法（VAS）和滤纸洇湿时间评定。结果：实验组口干程度VAS评分低于对照组（P〈0.01）,唾液分泌量高于对照组（P〈0.01）。结论：生脉饮加味疗法能有效预防鼻咽癌放疗时涎腺功能受损,口干症状减轻,生活质量提高。

Clinical research of Shengmaiyin Jiawei treating salivary gland damaged by nasopharyngeal carcinoma radiotherapy

Objective：To explore the effect of Shengmaiyin Jiawei in preventing salivary gland damaged by nasoparyngeal carcinoma radiotherapy. Methods：96 patients with nasopharyngeal carcinoma received curative radiotherapy were randomly divided into two groups：experiment group（radiotherapy and traditional and Chinese medicine） and control group（pure radiotherapy） . Total dose of radiotherapy was 60-70 Gy,6-7 weeks,conventional fractioned,radiotherapy field included face and neck coalition. The level of salivary gland damaged was checked by the visual analogue scale（VAS） and the time of waterish filter paper. Results：The VAS of the experimental group was less than the control group in the dryness of the mouth（P 〈0.01）;in the quantity of salivary secretion,the former was higher than the later（P 〈0.01） . Conclusion：Shengmaiyin Jiawei can prevent from salivary gland damaged and abate the symptom of dryness of the mouth effectively,and improve the quality of life.