江苏省男男性行为者HIV新发感染状况及影响因素研究

目的了解江苏省男男性行为者（menwhohavesexwithmen，MSM）HIV新发感染状况及影响因素。方法2011年在江苏省8个地级市招募MSM，并进行问卷调查及实验室检测，应用BEDHIV一1IgG捕获酶免疫（BED-CEIA）法检出其中的新发感染者，以HIV阴性MSM为对照，采用多因素Logistic回归模型分析HIV新发感染的影响因素。结果共招募2432名MSM，HIV新发感染率为4．67％（95％CI：3．44％～5．89％），HIV阴性和新发感染者之间在户籍省、文化程度、最近6个月是否与同性发生肛交、最近1次同性肛交是否使用安全套、最近6个月同性肛交安全套使用率及是否正在感染梅毒等变量上差异有统计学意义（均有P〈0．05），多因素分析外省籍、文化程度低、最近1次同性肛交未使用安全套及正在感染梅毒是MSM人群HIV新发感染的主要危险因素。结论江苏省MSM人群中HIV新发感染率较高，提示HIV在该人群中正快速传播，必须加大防控力度；影响新发感染的主要因素仍为无保护性肛交及正在感染梅毒等。

HIV incidence and its associated factors among men who have sex with men in Jiangsu Province

Objective To understand HIV incidence and its associated factors among men who have sex with men （MSM） in Jiangsu Province. Methods MSM were recruited for questionnaire interview and laboratory test and seroposi- tive samples were tested with BED HIV-1 IgG capture enzyme immunoassay（BED-CEIA） to detect recent HIV-1 infections. Multivariable Logistic regression model was used to analyze associated factors of HIV recent infection and HIV seronegative MSM as controls. Results A total of 2 432 MSM were recruited and HIV incidence was found to be 4. 67% （95% CI： 3.44%-5.89% ）. Household place, education level, Whether had anal sex with male sex partners and the frequency of condom use in the last 6 months, whether use condom in recent homosexual anal sex and whether infected with syphilis were significant different between HIV seronegative MSM and recent infections （ all P 〈 0.05 ）. Associated risk factors of HIV recent infection included immigrants from other provinces, low education level, recent homosexual anal sex without condom and syphilis infection. Conclusions High HIV incidence was shown among MSM in Jiangsu Province and had spread fast in this population. Powerful prevention and control efforts must be made. The main associated risk factors of HIV recent infection were still unprotected anal intercourse and svohilis infection.