| 不同分期肺癌组织中Beclin1、p53、p16表达情况分析 |
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| 引用本文： | 李晓颜,王桂琴. 不同分期肺癌组织中Beclin1、p53、p16表达情况分析[J]. 中国现代医生, 2010, 48(7): 26-27 |
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| 作者姓名： | 李晓颜 王桂琴 |
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| 作者单位： | 1. 山西医科大学附属汾阳医院,山西汾阳,032200
2. 山西医科大学微生物与免疫教研室,山西太原,030001 |
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| 摘 要： | 目的本文旨在通过对肺癌组织中Beclin1、p53和p16表达的分析,为肺癌早期诊断及其恶性度评估提供可靠数据。方法选择2009年1～12月在山西省汾阳医院就诊的肺癌患者,取肺组织50例,检测样本中不同分期肺癌组织Beclin1、p53、p16的表达情况,对该表达情况与对应的分期进行方差分析与ISD—f检验。结果不同肺癌分期的Beclinl、p53、p16的表达情况之间的差别有统计学意义（P〈0．05）。结论肺癌各临床分期的Beclin1、p53、p16表达情况不一样。随肺癌分期的增高p53表达量增高,p16表达量下调,Beclin1表达量降低。
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| 关 键 词： | 肺癌 Beclin1 p53 p16 |
Expression of Beclinl,p53 and p16 in Different Stages of Lung Cancer |
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| LI Xiaoyan,WANG Guiqin. Expression of Beclinl,p53 and p16 in Different Stages of Lung Cancer[J]. Journal China Modern Doctor, 2010, 48(7): 26-27 |
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| Authors: | LI Xiaoyan WANG Guiqin |
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| Affiliation: | LI Xiaoyan1 WANG Guiqin2 1.Affiliated Fenyang Hospital of Shanxi Medical University,Fenyang 032200,China,2.Teaching , Research Section of Microbiology , Immunology,Shanxi Medical University,Taiyuan 030001 |
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| Abstract: | Objective To investigate expression of Beclinl,p53 and p16 in lung cancer tissue of different stages and provide reliable data for early diagnosis of lung cancer and the assessment of its malignant degree. Methods We selected 50 patients with lung cancer from Shanxi Fengyang Hospital between Jan.2009 and Dec.2009. The expression levels of tissue Beclinl,p53 and p16 in different stages of lung cancer were detected and the analysis of variance and LSD-t test were used for their expression and their correspond... |
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| Keywords: | Beclin1 p53 p16 |
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