Non-nutritive sucking by infants exposed to pethidine in utero |
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Authors: | Hafström M Kjellmer I |
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Affiliation: | Department of Pediatrics, University of G?teborg, Sweden. mia.hafstrom@pediat.gu.se |
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Abstract: | Obstetric analgesia in the form of pethidine (meperidine) to mothers during delivery has adverse effects on some aspects of the behaviour of their newborn infants. The non-nutritive sucking (NNS) pattern of nine healthy full-term infants exposed to pethidine in utero was compared to that of a control group of infants. The pattern was analysed and quantified using an automatic computer-based method. The results are discussed in the context of endogenous and exogenous opiates and their effect on brain-stem rhythm generators. Conclusions: The typical NNS pattern with alternating sucking activity (bursts) and pauses is preserved in the exposed infants. There is a significantly lower sucking frequency (md 1.74 vs 1.90 Hz, p = 0.030*) and a tendency to a less stable rhythm in pethidine-exposed infants. |
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Keywords: | Infant non-nutritive sucking pethidine sucking |
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