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| 丹参水提液中丹酚酸B湿热降解动力学研究△ | |
| 引用本文： | 林青,黄琳,肖晓丽,陈薇,李楚源. 丹参水提液中丹酚酸B湿热降解动力学研究△[J]. 中国现代中药, 2008, 10(8): 29-31 |
| 作者姓名： | 林青 黄琳 肖晓丽 陈薇 李楚源 |
| 作者单位： | 广州白云山和记黄埔中药有限公司现代中药研究院,广东,广州,510515 |
| 基金项目： | 广东省广州市科技局科技攻关计划项目 |
| 摘 要： | 目的：研究丹参水提液中丹酚酸B的湿热降解动力学。方法：以HPLC测定不同温度不同加热时间丹参水提液中丹酚酸B湿热降解动力学相关参数。结果：丹参水提液中丹酚酸B湿热降解符合一级动力学。结论：缩短丹参水提、浓缩、干燥时间，尽快使丹参水提液固体化可减少丹酚酸B损失。 |
| 关 键 词： | 丹参 丹酚酸B 化学动力学 稳定性 |
| 收稿时间： | 2008-01-10 |
Kinetic Study on the Degradation of Salvianolic Acid B in Extract of [WTHX]Salvia miltiorrhiza Bge. |
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| Lin Qing,Huang Lin,Xiao Xiaoli,Chen Wei and Li Chuyuan. Kinetic Study on the Degradation of Salvianolic Acid B in Extract of [WTHX]Salvia miltiorrhiza Bge.[J]. Modern Chinese Medicine, 2008, 10(8): 29-31 | |
| Authors: | Lin Qing Huang Lin Xiao Xiaoli Chen Wei Li Chuyuan |
| Affiliation: | Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co., Guangzhou Guangdong 510515, China;Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co., Guangzhou Guangdong 510515, China;Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co., Guangzhou Guangdong 510515, China;Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co., Guangzhou Guangdong 510515, China;Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co., Guangzhou Guangdong 510515, China |
| Abstract: | Objective: To perform a kinetic analysis and formulation of the degradation kinetics of Salvianolic Acid B in Extract of Salvia miltiorrhiza Bge.. Methods: The extract of Salvia miltiorrhiza Bge. was incubated at different temperature, and the degradation kinetics of Salvianolic Acid B was determined by HPLC at suitable time intervals during incubation. Results: The degradation kinetics of Salvianolic Acid B in Extract of Salvia miltiorrhiza Bge. could be appropriately simulated by first order kinetics equation. Conclusion: Shorten extracting, concentrating and drying can reduce the losing of Salvianolic Acid B. |
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