| MTT法体外测定阴道毛滴虫药物敏感性 |
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| 引用本文： | 田春林 黄若密. MTT法体外测定阴道毛滴虫药物敏感性[J]. 应用预防医学, 1999, 5(5): 261-263 |
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| 作者姓名： | 田春林 黄若密 |
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| 作者单位： | 广西医科大学寄生虫学教研室!南宁530021 |
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| 摘 要： | 应用噻唑蓝（ＭＴＴ）吸鹛不度法体外测定两株阴道毛滴虫对甲硝唑（Ｍｅｔｒｏｎｉｄａｚｏｌｅ）和替硝唑（Ｔｉｎｉｄａｚｏｌｅ）的药物敏感性。结果显示：药物作用２４小时后，阴道毛滴虫对两种药物表现出不同的敏感性，对甲硝唑，甲、乙两株基本相同，而对替硝唑，乙株比甲株敏感。实验结果表明：本文人有简便快速、客观准确的优点，能较好地反映药物剂量效应关系，可用为临床用药筛选的方法。
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| 关 键 词： | MTT 阴道毛滴虫 药物敏感性 吸收光度法 |
A study of drug sensitivity of Trichomonas vaginalis using MTT in vitro |
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| Tian Chunlin,Huang Ruomi Guangxi Medical University,Nanning . A study of drug sensitivity of Trichomonas vaginalis using MTT in vitro[J]. Journal of Applied Preventive Medicine, 1999, 5(5): 261-263 |
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| Authors: | Tian Chunlin Huang Ruomi Guangxi Medical University Nanning |
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| Affiliation: | Tian Chunlin,Huang Ruomi Guangxi Medical University,Nanning 530021 |
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| Abstract: | The sensitivity of the Trichomonas vaginalis to metronidazole and tinidazole were assayed by MTT absorption spectrum method in vitro The results showed that,after 24 hour incubation with two drugs,the sensitivity of the T vaginalis was different,in metronidazole group,the sensitivity of strain A is similar to B,but strain B is better than A in tinidazole group The results indicated that this method was simple,rapid and accurate,it may better reflect dose effect relation and helpful for screening efficient drug in the treatment of the trichomoniasis |
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| Keywords: | MTT Trichomonas vaginalis Drug sensitivity |
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