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中国大耳白兔与罗曼母鸡对赭曲霉毒素A抗原免疫应答性的研究
引用本文:陈雪岚,许杨,熊勇华. 中国大耳白兔与罗曼母鸡对赭曲霉毒素A抗原免疫应答性的研究[J]. 卫生研究, 2003, 32(1): 24-26
作者姓名:陈雪岚  许杨  熊勇华
作者单位:中德联合研究院,南昌,330047
摘    要:
以中国大耳白兔及罗曼母鸡为免疫动物制备抗 赭曲霉毒素A抗体 ,比较了这两种动物的免疫应答进程。通过实验数据分析得出 ,中国大耳白兔对抗原的免疫应答较罗曼母鸡快 ,兔在抗原注射 30天左右就有明显的抗体产生 ,而鸡在 60天左右才有明显的抗体产生 ,且兔血清抗体效价达到最高峰时为鸡卵黄抗体的 3~ 4倍。

关 键 词:免疫应答  效价  间接非竞争ELISA(酶联免疫吸附法)  抗体
文章编号:1000-8020(2003)01-0024-03

Study on the immune response of big-ear white rabbit and Luoman hen to ochratoxin A
Chen Xuelan,Xu Yang,Xiong Yonghua Sino China Research Institute,Nanchang ,China. Study on the immune response of big-ear white rabbit and Luoman hen to ochratoxin A[J]. Journal of hygiene research, 2003, 32(1): 24-26
Authors:Chen Xuelan  Xu Yang  Xiong Yonghua Sino China Research Institute  Nanchang   China
Affiliation:Sino-China Research Institute, Nanchang 330047, China.
Abstract:
Antibodies of anti ochratoxin A (anti OTA) were prepared by immunizing white rabbits and Luoman hens. The immune responses to OTA of these two animals were compared. It was concluded that the immune response of white rabbits was faster than Luoman hens'. The anti OTA IgG of rabbits was produced after 30d while the anti OTA IgY was produced after 60d. The top titre of anti OTA IgG was 3-4 times of the titre of anti OTA IgY's.
Keywords:immune response   titre   competitive indirect ELISA   anti body  
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