| 环状RNA与妊娠期特有疾病 |
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| 引用本文： | 郭玉萍,范翠芳.环状RNA与妊娠期特有疾病[J].中国优生与遗传杂志,2020(1):3-6. |
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| 作者姓名： | 郭玉萍 范翠芳 |
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| 作者单位： | 武汉大学人民医院产科 |
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| 摘 要： | 环状RNA(CircRNA)是一类特殊的、具有共价闭合环状结构的内源非编码 RNA,在疾病中具有重要的生物学功能。多项研究表明,环状RNA(CircRNAs)与妊娠期特有疾病的发生发展密切相关,可作为疾病诊断或判断预后的预测生物标记物。本文对环状RNA(CircRNAs)在妊娠期特有疾病中的子痫前期及妊娠期糖尿病的发生机制中的研究现状和最新进展进行综述。
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| 关 键 词： | 环状RNA 子痫前期 妊娠期糖尿病 生物标记物 |
Circular RNA in specifi c diseases during pregnancy |
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| GUO Yu-ping,FAN Cui-fang.Circular RNA in specifi c diseases during pregnancy[J].Chinese Journal of Birth Health & Heredity,2020(1):3-6. |
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| Authors: | GUO Yu-ping FAN Cui-fang |
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| Institution: | (Department of Obstetrics,People's Hospital of Wuhan University,Wuhan Hubei 430000 China) |
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| Abstract: | Circular RNAs are a special class of endogenous non-coding RNA with covalently closed circular structures.Circular RNA(CircRNA)has important biological functions in diseases.A number of studies have shown that circular RNAs(CircRNAs)are closely related to the development of specific diseases during pregnancy and can be used as predictive biomarkers for disease diagnosis or prognosis.This review focuses on the research status and research progress of circular RNA(CircRNAs)in the pathogenesis of Pregnancy-specific diseases which included pre-eclampsia and gestational diabetes. |
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| Keywords: | Circular RNAs Pre-eclampsia Gestational diabetes Biomarkers |
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