平肝定眩汤治疗肝阳上亢型后循环缺血性眩晕60例临床观察

目的:观察平肝定眩汤对肝阳上亢型后循环缺血性眩晕的疗效。方法:选取2017年6月-2018年10月烟台业达医院收治的后循环缺血性眩晕的患者120例,按随机数字表法分为治疗组和对照组。治疗组和对照组各60例,两组一般的资料经统计学方法,差异无统计学意义(P>0.05),具有可比性。两组均给予改善循环,控制血压、血糖,调节血脂,抗血小板聚集等基础治疗。治疗组给予平肝定眩汤,对照组给予平眩胶囊。两组疗程均为4周,观察两组患者治疗前后总体症状,脑血流速度、血脂、血糖等指标改善情况。采用SPSS 11.0统计学软件进行计算。结果:治疗组总有效率91.7%(55/60),对照组总有效率61.6%(37/60),两组疗效比较有统计学意义(P<0.05)。治疗组三酰甘油(Triglyceride,TG)、血清总胆固醇(Serum Total Cholesterol,TC)、HDL-C、LDL-C治疗后显著改善,与治疗前比较,差异有统计学意义(P<0.05);对照组TG及TC治疗前后差异有统计学意义(P<0.05),高密度脂蛋白胆固醇(High Density Liptein Cholesterol,HDL-C)及低密度脂蛋白胆固醇(Low Density Liptein Cholesterol,LDL-C)治疗前后比较,差异无统计学意义(P>0.05)。两组治疗后TC比较,差异有统计学意义(P<0.05)。两组治疗后空腹血糖(Fasting Plasma Glucose,GLU)明显降低(P<0.05),两组间的治疗后比较,差异无统计学意义(P>0.05)。治疗组治疗后椎动脉(Vertebral Artery,VA)、基底动脉(Basilarartery,BA)平均血流速度(Mean Blood Flow Velocity,VM)明显提高,与对照组治疗后相比较,差异具有统计学意义(P<0.05)。结论:平肝定眩汤治疗后循环缺血性眩晕在改善患者症状、降低血液黏稠度,改善脑血流状况方面疗效显著。

Clinical observation of Pinggan Dingxuan Decoction in the treatment of60 cases of posterior circulation ischemic vertigodue to hyperactivity of liver Yang

Objective:To observe the curative effect of Pinggan Dingxuan Decoction(平肝定眩汤)on posterior circulation ischemic vertigo of hyperactivity of liver yang.Methods:120 patients with posterior circulation ischemic vertigo admitted to our hospital from June 2017 to October 2018 were randomly divided into the treatment group and the control group.There were 60 cases in the treatment group and 60 cases in the control group.The general data of the two groups had no statistical significance(P>0.05),which was comparable.Both groups were given basic treatment such as improving circulation,controlling blood pressure and blood sugar,regulating blood lipid and anti-platelet aggregation.The treatment group was given Pinggan Dingxuan Decoction and the control group was given Pingxuan Capsule.Both groups were treated for 4 weeks.The general symptoms,cerebral blood flow velocity,blood lipid and blood sugar were observed before and after treatment.SPSS11.0 statistical software was used to calculate the total effective rate.Results:The total effective rate of the treatment group was 91.7%(55/60),and that of the control group was 61.6%(37/60).There was statistical significance between the two groups(P<0.05).In the treatment group,TG,TC,HDL-C and LDL-C were significantly improved after treatment,compared with that before treatment,the difference was statistically significant(P<0.05).There were significant differences in TG and TC before and after treatment in the control group(P<0.05).There was no significant difference in HDL-C and LDL-C before and after treatment(P>0.05).TC of the two groups after treatment was significantly different(P<0.05).The FPG of the two groups decreased significantly after treatment(P<0.05).There was no significant difference between the two groups after treatment(P>0.05).The average blood flow velocity(VM)of VA and BA in the treatment group was significantly higher than that in the control group(P<0.05).Conclusion:Pinggan Dingxuan Decoction is effective in improving symptoms,blood viscosity and cerebral blood flow in patients with circulatory ischemic vertigo after treatment.