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| 溴隐亭治疗泌乳素大腺瘤的临床观察 | |
| 引用本文： | 蔡梅钦,秦峰,陈海燕,凌聪,何海勇,郭英. 溴隐亭治疗泌乳素大腺瘤的临床观察[J]. 中国医院药学杂志, 2011, 0(15) |
| 作者姓名： | 蔡梅钦 秦峰 陈海燕 凌聪 何海勇 郭英 |
| 作者单位： | 中山大学附属第三医院神经外科;中山大学附属第三医院皮肤科; |
| 摘 要： | 目的:探讨溴隐亭治疗泌乳素大腺瘤的方法、效果及不良反应。方法:回顾性分析单纯溴隐亭治疗9例泌乳素大腺瘤的长期随访结果。结果:溴隐亭的开始剂量为1.25～2.5 mg.d-1、分2～3次口服,在6个月内缓慢增至5～15 mg.d-1。平均随访58.3个月,最后随访时血泌乳素(prolactine,PRL)恢复正常8例(88.89%)、肿瘤体积平均缩小(81.3±23.9)%。治疗期间大部分原发症状好转,出现头晕2例、脑脊液漏1例。结论:溴隐亭单药治疗泌乳素大腺瘤能明显降低血PRL、缩小肿瘤体积及改善临床症状,且不良反应少。 |
| 关 键 词： | 溴隐亭 泌乳素大腺瘤 |
Efficacy and safety of bromocriptine as first line treatment for macroprolactinoma |
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| CAI Mei-qin,QIN Feng,CHEN Hai-yan,LING Cong,HE Hai-yong,GUO Ying. Efficacy and safety of bromocriptine as first line treatment for macroprolactinoma[J]. Chinese Journal of Hospital Pharmacy, 2011, 0(15) | |
| Authors: | CAI Mei-qin QIN Feng CHEN Hai-yan LING Cong HE Hai-yong GUO Ying |
| Affiliation: | CAI Mei-qin1,QIN Feng1,CHEN Hai-yan2,LING Cong1,HE Hai-yong1,GUO Ying1(1.Department of Neurosurgery and Pituitary Adenoma Center,2.Department of Dermatology,the Third Affiliated Hospital,Sun Yat-Sen University,Guangdong Guangzhou 510630,China) |
| Abstract: | OBJECTIVE To investigate the methods,efficacy and safety of bromocriptine as first line treatment for macroprolactinoma.METHODS Retrospectivly analyse the long-term follow-up datas of 9 cases of macroprolactinoma treated with bromocriptine.RESULTS Bromocriptine was initiated with a dose of 0.625~1.25 mg daily given in twice or thrice,and a dose generally of 5-15 mg daily was gradually reached in 6 months.In the mean follow-up period of 58.3 months,8 patients have normalized their prolactin levels,the mean r... |
| Keywords: | bromocriptine macroplactinoma |
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