| 胰激肽原酶联合甲钴胺治疗糖尿病周围神经病变的疗效观察 |
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| 引用本文： | 张朝云,王辉,赵玉珍,任康,毕长华,张信. 胰激肽原酶联合甲钴胺治疗糖尿病周围神经病变的疗效观察[J]. 中国医院药学杂志, 2011, 0(15) |
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| 作者姓名： | 张朝云 王辉 赵玉珍 任康 毕长华 张信 |
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| 作者单位： | 中石油中心医院内分泌科; |
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| 摘 要： | 目的:观察胰激肽原酶与甲钴胺联合应用治疗糖尿病周围神经病变的疗效。方法:60例糖尿病周围神经病变患者随机分为治疗组及对照组,在常规治疗的基础上,治疗组用胰激肽原酶联合甲钴胺治疗,对照组用甲钴胺治疗,12周后进行疗效评定。结果:治疗组与治疗前比较,临床症状和体征明显改善,正中神经、尺神经及胫神经的运动神经传导速度(MCV)、感觉神经传导速度(SCV)显著增加(P<0.05);治疗组与对照组作治疗后比较,差异具有显著性(P<0.01)。结论:胰激肽原酶联合甲钴胺治疗糖尿病周围神经病变优于单用甲钴胺,疗效显著。
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| 关 键 词： | 胰激肽原酶 甲钴胺 糖尿病周围神经病变 |
Clinical observation of pancreatic kininogenase combined with mecobalamin treating diabetic peripheral neuropathy |
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| ZHANG Chao-yun,WANG Hui,ZHAO Yu-zhen,REN Kang,BI Chang-hua,ZHANG Xin. Clinical observation of pancreatic kininogenase combined with mecobalamin treating diabetic peripheral neuropathy[J]. Chinese Journal of Hospital Pharmacy, 2011, 0(15) |
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| Authors: | ZHANG Chao-yun WANG Hui ZHAO Yu-zhen REN Kang BI Chang-hua ZHANG Xin |
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| Affiliation: | ZHANG Chao-yun,WANG Hui,ZHAO Yu-zhen,REN Kang,BI Chang-hua,ZHANG Xin(Department of Endocrinology,Central Hospital of China National Petroleum Corporation,Hebei Langfang 065000,China) |
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| Abstract: | OBJECTIVE To observe the therapeutic effects of pancreatic kininogenase(Yikai) combined with mecobalamin on diabetic peripheral neuropathy(DPN).METHODS Sixty DPN patients were randomly divided into the treatment group and the control group.On the basis of conventional treatment,the patients of treatment group were given with pancreatic kininogenase combined with mecobalamin,while the patients of control group were given with mecobalamin alone.After twelve weeks,the therapeutic effects were evaluated.RESULTS... |
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| Keywords: | pancreatic kininogenase(Yikai) mecobalamin diabetic peripheral neuropath |
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