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地佐辛复合丙泊酚在自凝刀射频治疗子宫肌瘤中的应用研究
引用本文:陈佳颖,佟波涛,赵建生,徐萍萍. 地佐辛复合丙泊酚在自凝刀射频治疗子宫肌瘤中的应用研究[J]. 中国医院药学杂志, 2011, 0(18)
作者姓名:陈佳颖  佟波涛  赵建生  徐萍萍
作者单位:中国人民解放军第81医院麻醉科;中国人民解放军第81医院妇产科;
摘    要:目的:探讨地佐辛复合丙泊酚用于自凝刀射频治疗子宫肌瘤的安全性和有效性。方法:40例子宫肌瘤患者在自凝刀射频消融过程中给予地佐辛复合丙泊酚全凭静脉麻醉,观察用药前后生命体征,不良反应及术后VAS和Ramsay评分。结果:(1)用药前后平均动脉压、心率、血氧饱和度、呼吸频率均略有下降,差异有统计学意义(P<0.05),但仍在正常范围。(2)VAS评分,术后15 min为(0.9±1.0)分,并分别与0.5,1,2 h时评分比较,差异无统计学意义。(3)Ramsay评分,术后15 min为(2.4±0.5)分,术后1,2 h所有患者均评为2分,达到离开术后恢复室标准。结论:地佐辛复合丙泊酚全凭静脉麻醉方案用于自凝刀射频治疗子宫肌瘤手术,能达到术中良好的镇静镇痛效果,有效抑制应激反应,稳定血流动力学,并能在术后提供有效的镇痛作用,是一种安全有效的麻醉方案。

关 键 词:地佐辛  丙泊酚  射频技术  子宫肌瘤  

Application of propofor combined with dezocine in radiofrequency therapy on uterine leiomyoma
CHEN Jia-ying,TONG Bo-tao,ZHAO Jian-sheng,XU Ping-ping. Application of propofor combined with dezocine in radiofrequency therapy on uterine leiomyoma[J]. Chinese Journal of Hospital Pharmacy, 2011, 0(18)
Authors:CHEN Jia-ying  TONG Bo-tao  ZHAO Jian-sheng  XU Ping-ping
Affiliation:CHEN Jia-ying1,TONG Bo-tao1,ZHAO Jian-sheng1,XU Ping-ping2(1.Department of Anesthesiology,2.Department of Obstetrics and Gynecology,The 81st PLA Hospital,Jiangsu Nanjing 210002,China)
Abstract:OBJECTIVE To evaluate the effect and safety of propofol combined with dezocine in radiofrequency therapy on uterine leiomyoma.METHODS 40 patients were given radiofrequency therapy on uterine leiomyoma with propofol combined with dezocine.The changes of vital sign,conscious-sedation,and pain score were assessed.RESULTS All of 40 patients underwent radiofrequency therapy completely,and each patient could tolerate the procedure well.(1)There was significant difference in mean arterial blood pressure(MAP),heart...
Keywords:propofol  dezocine  radiofrequency therapy  uterine leiomyoma  
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