罕见鼻部皮肤肌纤维瘤1例

皮肤肌纤维瘤是一种少见的良性皮肤软组织肿瘤，病变为成纤维细胞和肌成纤维细胞增殖，常见于年 轻成年人和青少年的肩部及颈部，其次好发于上臂、大腿、胸壁、背部、腋窝和腹部。本文报道1例罕见发生于鼻 部的皮肤肌纤维瘤，此例肿物表现为无症状的坚硬的皮肤结节，病理上证实与皮肤肌纤维瘤相符。免疫组织化学 结果显示，肿瘤细胞表达波形蛋白(vimentin)、肌特异性肌动蛋白(HHF35)和平滑肌肌动蛋白(α-smooth muscle actin， α-SMA)。手术切除后随访2年无复发。

A rare case report for dermatomyofibroma in nasion

Dermatomyofi broma is a benign and rare proliferation of myofi broblasts and fi broblasts of the skin. Dermatomyofi broma commonly locates at the shoulder and neck of young adults and adolescents. Other frequently affected anatomic sites are upper arms, thigh, chest wall, back, axillary region and abdomen. Herein, we reported a case of dermatomyofibroma occurred in the nasion. The asymptomatic fi rm nodule and histopathological features were consistent with dermatomyofi broma. Immunohistochemically, the tumor cells expressed vimentin, HHF35 and α-smooth muscle actin (α-SMA). Th e patient was followed up for 2 years aft er excision of the tumors and recurrences were not observed.