肺腺鳞癌的临床病理分析

目的 总结探讨肺腺鳞癌的临床病理特点，以进一步改善肺腺鳞癌的疗效。方法对本院1994年1月至2004年12月经手术治疗的63例肺腺鳞癌患者临床、病理资料进行同顾性分析，并结合文献讨论其组织学来源、发病率以及治疗和预后。结果全组占同期手术的11．5％，施行肺叶切除（含两肺叶切除、支气管袖状切除）47例．全肺切除16例，其中根治性切除58例，姑息性切除5例；术前确诊12例；TNM分期：Ⅰ期11例，Ⅱ期14例，Ⅲ期37例，Ⅳ期1例。全组有淋巴结转移者49例，转移率77．8％；淋巴结转移度43．9%。结论 肺腺鳞癌已成为临床常见的肺肿瘤，恶性程度较高，预后差。应采取以手术为主的综合治疗。

Clinicopathological characteristics of lung adenosquamous carcinoma

Objective To improve the effectiveness of treatment of lung adenosquamous carcinoma,the clinicopathological characteristics of lung adenosquamous carcinoma were reviewed.Methods From Jan.1994 to Dec.2004,63 patients of primary lung adenosquamous carcinoma were treated chiefly by operation.Results Lung adenosquamous carcinoma comprised 11.5% of total patients surgically treated for the primary lung cancer during the same time.12 cases were diagnosed before operation.49 cases had lymph nodes metastasis(LNM)(77.8%).The degree of LNM was 43.9%.Conclusion Our results suggest that adenosquamous carcinoma has become a common histological type of lung carcinoma.It is a more virulent tumor,which exhibits highly aggressive biological behavior and higher rate of lymph node metastasis(77.8%).Its prognosis is worse than other NSCLC.With surgical treatment as the chief managemnt,it should be treated with multi-modality therapy.