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IgG4相关性肾病研究进展
引用本文:李正东 杜晓刚. IgG4相关性肾病研究进展[J]. 中华临床医师杂志(电子版), 2014, 0(3): 538-541
作者姓名:李正东 杜晓刚
作者单位:重庆医科大学附属第一医院肾内科,400016
摘    要:
IgG4相关性肾病(IgG4-RKD)是近年来发现的一种自身免疫性疾病,多表现为急性或慢性肾功能不全、蛋白尿,血清IgG4升高,影像学上可见肾实质损害,组织病理表现为小管间质性肾炎,以间质大量IgG4阳性浆细胞浸润为主要特征,对糖皮质激素治疗反应较好。本文将对IgG4-RKD的临床诊治进展作一综述。

关 键 词:肾炎,间质性  IgG4相关性肾病

The research progress of IgG4-related kidney disease
Li Zhengdong,Du Xiaogang. The research progress of IgG4-related kidney disease[J]. Chinese Journal of Clinicians(Electronic Version), 2014, 0(3): 538-541
Authors:Li Zhengdong  Du Xiaogang
Affiliation:. (Department of Nephrology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China)
Abstract:
IgG4-related kidney diseases is an autoimmune disease that was found in recent years, which can present with acute or chronic renal insufficiency and proteinuria and high level of serum IgG4. Iconography examination always shows a renal organic lesions. Tubulointerstitial nephritis with dense infiltration of IgG4-positive plasma cells is the classic pathological feature. This disease alway responds to steroid therapy with a good effect. This review will focus on the progress of clinical diagnose and treatment for IgG4-related kidney diseases.
Keywords:Nephritis  interstitial  IgG4-related kidney disease
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